Mechanism of action of ribosomally synthesized and post-translationally modified peptides
C Ongpipattanakul, EK Desormeaux… - Chemical …, 2022 - ACS Publications
Ribosomally synthesized and post-translationally modified peptides (RiPPs) are a natural
product class that has undergone significant expansion due to the rapid growth in genome …
product class that has undergone significant expansion due to the rapid growth in genome …
Emerging diversity in lipid–protein interactions
Membrane lipids interact with proteins in a variety of ways, ranging from providing a stable
membrane environment for proteins to being embedded in to detailed roles in complicated …
membrane environment for proteins to being embedded in to detailed roles in complicated …
A scalable platform to discover antimicrobials of ribosomal origin
RS Ayikpoe, C Shi, AJ Battiste, SM Eslami… - Nature …, 2022 - nature.com
Ribosomally synthesized and post-translationally modified peptides (RiPPs) are a promising
source of new antimicrobials in the face of rising antibiotic resistance. Here, we report a …
source of new antimicrobials in the face of rising antibiotic resistance. Here, we report a …
Antibacterial activities of bacteriocins: application in foods and pharmaceuticals
SC Yang, CH Lin, CT Sung, JY Fang - Frontiers in microbiology, 2014 - frontiersin.org
Bacteriocins are a kind of ribosomal synthesized antimicrobial peptides produced by
bacteria, which can kill or inhibit bacterial strains closely-related or non-related to produced …
bacteria, which can kill or inhibit bacterial strains closely-related or non-related to produced …
Ribosomally synthesized and post-translationally modified peptide natural products: overview and recommendations for a universal nomenclature
Covering: 1988 to 2012 This review presents recommended nomenclature for the
biosynthesis of ribosomally synthesized and post-translationally modified peptides (RiPPs) …
biosynthesis of ribosomally synthesized and post-translationally modified peptides (RiPPs) …
Gut microbiota as a source of novel antimicrobials
ABSTRACT Bacteria, Archaea, Eukarya and viruses coexist in the human gut, and this
coexistence is functionally balanced by symbiotic or antagonistic relationships. Antagonism …
coexistence is functionally balanced by symbiotic or antagonistic relationships. Antagonism …
Dynamic covalent self-assembly of mechanically interlocked molecules solely made from peptides
HV Schröder, Y Zhang, AJ Link - Nature chemistry, 2021 - nature.com
Mechanically interlocked molecules (MIMs), such as rotaxanes and catenanes, have
captured the attention of chemists both from a synthetic perspective and because of their …
captured the attention of chemists both from a synthetic perspective and because of their …
Lasso peptides: an intriguing class of bacterial natural products
JD Hegemann, M Zimmermann, X Xie… - Accounts of chemical …, 2015 - ACS Publications
Conspectus Natural products of peptidic origin often represent a rich source of medically
relevant compounds. The synthesis of such polypeptides in nature is either initiated by …
relevant compounds. The synthesis of such polypeptides in nature is either initiated by …
Machine learning and data science in soft materials engineering
AL Ferguson - Journal of Physics: Condensed Matter, 2017 - iopscience.iop.org
In many branches of materials science it is now routine to generate data sets of such large
size and dimensionality that conventional methods of analysis fail. Paradigms and tools from …
size and dimensionality that conventional methods of analysis fail. Paradigms and tools from …
Production of bioactive substances by intestinal bacteria as a basis for explaining probiotic mechanisms: bacteriocins and conjugated linoleic acid
The mechanisms by which intestinal bacteria achieve their associated health benefits can
be complex and multifaceted. In this respect, the diverse microbial composition of the human …
be complex and multifaceted. In this respect, the diverse microbial composition of the human …