Emergence, transmission dynamics and mechanisms of artemisinin partial resistance in malaria parasites in Africa
PJ Rosenthal, V Asua, MD Conrad - Nature Reviews Microbiology, 2024 - nature.com
Malaria, mostly due to Plasmodium falciparum infection in Africa, remains one of the most
important infectious diseases in the world. Standard treatment for uncomplicated P …
important infectious diseases in the world. Standard treatment for uncomplicated P …
Evidence for a role of Anopheles stephensi in the spread of drug- and diagnosis-resistant malaria in Africa
Anopheles stephensi, an Asian malaria vector, continues to expand across Africa. The
vector is now firmly established in urban settings in the Horn of Africa. Its presence in areas …
vector is now firmly established in urban settings in the Horn of Africa. Its presence in areas …
Towards next-generation treatment options to combat Plasmodium falciparum malaria
Malaria, which is caused by infection of red blood cells with Plasmodium parasites, can be
fatal in non-immune individuals if left untreated. The recent approval of the pre-erythrocytic …
fatal in non-immune individuals if left untreated. The recent approval of the pre-erythrocytic …
Subcutaneous administration of a monoclonal antibody to prevent malaria
K Kayentao, A Ongoiba, AC Preston… - … England Journal of …, 2024 - Mass Medical Soc
Background Subcutaneous administration of the monoclonal antibody L9LS protected adults
against controlled Plasmodium falciparum infection in a phase 1 trial. Whether a monoclonal …
against controlled Plasmodium falciparum infection in a phase 1 trial. Whether a monoclonal …
[图书][B] World malaria report 2023
World Health Organization - 2023 - books.google.com
Page 1 World malaria וייוייו report 2023 wwwwww World Health Organization Page 2 World
malaria report 2023 ISBN 978-92-4-008617-3 (electronic version) ISBN 978-92-4-008618-0 …
malaria report 2023 ISBN 978-92-4-008617-3 (electronic version) ISBN 978-92-4-008618-0 …
Evidence of artemisinin partial resistance in northwestern Tanzania: clinical and molecular markers of resistance
Background In 2021, nationwide malaria molecular surveillance revealed a high prevalence
of a validated artemisinin resistance marker, the kelch13 (k13) Arg561His mutation, in the …
of a validated artemisinin resistance marker, the kelch13 (k13) Arg561His mutation, in the …
Artemisinin-resistant malaria in Africa demands urgent action
Artemisinin derivatives are the cornerstone of current antimalarial treatment, both for severe
malaria (injectable artesunate) and uncomplicated malaria [artemisinin combination therapy …
malaria (injectable artesunate) and uncomplicated malaria [artemisinin combination therapy …
Prevalence of mutations associated with artemisinin partial resistance and sulfadoxine–pyrimethamine resistance in 13 regions in Tanzania in 2021: a cross-sectional …
Background The emergence of the artemisinin partial resistance (ART-R) mutation in the
Plasmodium falciparum kelch13 gene (k13), Arg561His, in Rwanda and the regional …
Plasmodium falciparum kelch13 gene (k13), Arg561His, in Rwanda and the regional …
Population genomics and transcriptomics of Plasmodium falciparum in Cambodia and Vietnam uncover key components of the artemisinin resistance genetic …
The emergence of Plasmodium falciparum parasites resistant to artemisinins compromises
the efficacy of Artemisinin Combination Therapies (ACTs), the global first-line malaria …
the efficacy of Artemisinin Combination Therapies (ACTs), the global first-line malaria …
Treatment Failure in a UK Malaria Patient Harboring Genetically Variant Plasmodium falciparum From Uganda With Reduced In Vitro Susceptibility to Artemisinin and …
Background Recent cases of clinical failure in malaria patients in the United Kingdom (UK)
treated with artemether-lumefantrine have implications for malaria chemotherapy worldwide …
treated with artemether-lumefantrine have implications for malaria chemotherapy worldwide …