Immunodeficient mice engrafted with functional human cells and tissues, that is, humanized
mice, have become increasingly important as small, preclinical animal models for the study …

At least 20 million hepatitis E virus (HEV) infections occur annually, with> 3 million
symptomatic cases and∼ 60,000 fatalities. Hepatitis E is generally self-limiting, with a case …

Intelligent fault diagnosis techniques have replaced time-consuming and unreliable human
analysis, increasing the efficiency of fault diagnosis. Deep learning models can improve the …

RNA viruses have evolved elaborate strategies to protect their genomes, including 5′
capping. However, until now no RNA 5′ cap has been identified for hepatitis C virus,(HCV) …

Significant advances in our understanding of the in vivo functions of human cells and tissues
and the human immune system have resulted from the development of'humanized'mouse …

Nonalcoholic fatty liver disease (NAFLD) is the most prevalent liver disease worldwide. It
encompasses a spectrum ranging from simple steatosis to fatty liver with hepatocellular …

More than two decades of intense research has provided a detailed understanding of
hepatitis C virus (HCV), which chronically infects 2% of the world's population. This effort has …

The discovery of hepatitis C virus (HCV) in 1989 permitted basic research to unravel critical
components of a complex life cycle for this important human pathogen. HCV is a highly …

Tissue engineering can be used to restore, maintain, or enhance tissues and organs. The
potential impact of this field, however, is far broader—in the future, engineered tissues could …

The complexity of organogenesis hinders in vitro generation of organs derived from a
patient's pluripotent stem cells (PSCs), an ultimate goal of regenerative medicine. Mouse …