Obesity and ageing place a tremendous strain on the global healthcare system. Age-related
sarcopenia is characterized by decreased muscular strength, decreased muscle quantity …

Physical exercise has beneficial effects on metabolic diseases, and a combined therapeutic
regimen of regular exercise and pharmaceutical treatment is often recommended for their …

Exercise is recognized by clinicians in the field of clinical oncology for its potential role in
reducing the risk of certain cancers and in reducing the risk of disease recurrence and …

The myokine irisin is supposed to be cleaved from a transmembrane precursor, FNDC5
(fibronectin type III domain containing 5) and to mediate beneficial effects of exercise on …

Irisin is an exercise-induced myokine expressed as a bioactive peptide in multiple tissues
and organs, and exercise and cold exposure are the major inducers for its secretion. Irisin …

Sedentary life style is considered to be an independent risk factor for many disorders,
including development of type 2 diabetes, obesity, immune dysfunction, asthma, and …

Irisin is a hormone-like molecule mainly released by skeletal muscles in response to
exercise. Irisin induces browning of the white adipose tissue and has been shown to …

Objective We determined detailed time-course changes in the irisin response to acute
exercise using different exercise modes. Methods In experiment 1, seven healthy males …

Background It has been shown that irisin levels are reduced in skeletal muscle and plasma
of obese rats; however, the effect of exercise training on irisin level remains controversial …

Irisin is a recently discovered myokine that increases adipocyte metabolism, induces further
“browning” of white adipose tissue, and enhances glucose metabolism. No study has ever …