Cholangiocytes, the epithelial cells lining the intrahepatic and extrahepatic bile ducts, are
highly specialized cells residing in a complex anatomic niche where they participate in bile …

Connection between inflammation and cancer is a rapidly developing field. Epidemiological
data suggests that inflammation along with distinct arms of host immune system plays a very …

The use of probiotics and synbiotics in the food industry or as food supplements for a
balanced diet and improved gut homeostasis has been blooming for the past decade. As …

Autosomal dominant polycystic kidney disease is the most prevalent, potentially lethal,
monogenic disorder. It is associated with large interfamilial and intrafamilial variability, which …

Diverse commensal populations are now regarded as key to physiological homeostasis and
protection against disease. Although bacteria are the most abundant component of …

Sexual dimorphism is associated not only with somatic and behavioral differences between
men and women, but also with physiological differences reflected in organ metabolism …

Autosomal dominant polycystic kidney disease is the most prevalent, potentially lethal
monogenic disorder. It has large inter-and intra-familial variability explained to a large extent …

Primary biliary cirrhosis (PBC) is an autoimmune disease characterized by clinical
homogeneity among patients, an overwhelming female predominance, production of a …

There is extensive evidence supporting the interplay between metabolism and immune
response, that have evolved in close relationship, sharing regulatory molecules and …

Non-alcoholic fatty liver disease (NAFLD) is a major health issue worldwide, being
frequently associated with obesity, unbalanced dietary regimens, and reduced physical …