Hidradenitis suppurativa (HS) is a chronic inflammatory skin disease that severely impairs
patients' quality of life. It is characterized by recurrent painful nodules, abscesses and …

A family history of hidradenitis suppurativa (HS) is reported by about one-third of patients,
and the pattern of inheritance suggests a single gene disorder inherited as an autosomal …

Hidradenitis suppurativa (HS) is a chronic, debilitating, inflammatory skin disorder with a
prevalence of around 1% and a profound impact on patients' quality of life. Characteristic …

Two phase-III clinical trials with anti-amyloid peptide antibodies have met their primary goal,
ie slowing of Alzheimer's disease (AD) progression. However, antibody therapy may not be …

The rising prevalence of Alzheimer's disease (AD), together with the lack of effective
treatments, portray it as one of the major health challenges of our times. Untangling AD …

Hidradenitis suppurativa (HS) is a chronic dermatosis characterized by nodules and
abscesses in apocrine gland-bearing sites. Mutations in three gamma-secretase complex …

Hidradenitis suppurativa (HS) is a severe chronic inflammatory disorder characterized by
recurrent painful deep‐seated nodules with a predilection to the apocrine‐bearing areas of …

The presenilin (PS) proteins exert a crucial role in the pathogenesis of Alzheimer disease
(AD) by mediating the intramembranous cleavage of amyloid precursor protein (APP) and …

Background Acne inversa (AI) is a chronic inflammatory skin disease with an autosomal
dominant inheritance pattern. Mutations of the gene encoding nicastrin (NCSTN), a cofactor …

Acne and hidradenitis suppurativa (HS) both centre on hair follicles. They often occur
together as part of the acne tetrad, but are found in distinct localizations. Acne is primarily …