[HTML][HTML] Stimuli-responsive liposomal nanoformulations in cancer therapy: Pre-clinical & clinical approaches

M Ashrafizadeh, M Delfi, A Zarrabi, A Bigham… - Journal of controlled …, 2022 - Elsevier
The site-specific delivery of antitumor agents is of importance for providing effective cancer
suppression. Poor bioavailability of anticancer compounds and the presence of biological …

Stimuli-responsive nano-architecture drug-delivery systems to solid tumor micromilieu: past, present, and future perspectives

HS El-Sawy, AM Al-Abd, TA Ahmed, KM El-Say… - ACS …, 2018 - ACS Publications
The microenvironment characteristics of solid tumors, renowned as barriers that harshly
impeded many drug-delivery approaches, were precisely studied, investigated, categorized …

New developments in liposomal drug delivery

BS Pattni, VV Chupin, VP Torchilin - Chemical reviews, 2015 - ACS Publications
New Developments in Liposomal Drug Delivery | Chemical Reviews ACS ACS Publications
C&EN CAS Find my institution Log In Chemical Reviews ACS Publications. Most Trusted. Most …

Surface modification strategies in translocating nano-vesicles across different barriers and the role of bio-vesicles in improving anticancer therapy

P Tiwari, K Yadav, RP Shukla, S Gautam… - Journal of Controlled …, 2023 - Elsevier
Nanovesicles and bio-vesicles (BVs) have emerged as promising tools to achieve targeted
cancer therapy due to their ability to overcome many of the key challenges currently being …

[HTML][HTML] Multifunctional, stimuli-sensitive nanoparticulate systems for drug delivery

VP Torchilin - Nature reviews Drug discovery, 2014 - nature.com
The use of nanoparticulate pharmaceutical drug delivery systems (NDDSs) to enhance the
in vivo effectiveness of drugs is now well established. The development of multifunctional …

Barriers to drug delivery in solid tumors

SK Sriraman, B Aryasomayajula, VP Torchilin - Tissue barriers, 2014 - Taylor & Francis
Over the last decade, significant progress has been made in the field of drug delivery. The
advent of engineered nanoparticles has allowed us to circumvent the initial limitations to …

Liposomal doxorubicin as targeted delivery platform: Current trends in surface functionalization

V Makwana, J Karanjia, T Haselhorst… - International Journal of …, 2021 - Elsevier
Liposomal delivery systems have significantly enhanced the efficacy and safety of
chemotherapeutic agents compared to free (non-liposomal) formulations. Liposomes are …

Recent in vivo advances in cell-penetrating peptide-assisted drug delivery

K Kurrikoff, M Gestin, Ü Langel - Expert opinion on drug delivery, 2016 - Taylor & Francis
Introduction: Delivery of macromolecular drugs is an important field in medical research.
However, macromolecules are usually unable to cross the cell membrane without the …

Intracellular delivery of nanocarriers and targeting to subcellular organelles

A Jhaveri, V Torchilin - Expert opinion on drug delivery, 2016 - Taylor & Francis
Introduction: Recent trends in drug delivery indicate a steady increase in the use of targeted
therapeutics to enhance the specific delivery of biologically active payloads to diseased …

DePEGylation strategies to increase cancer nanomedicine efficacy

L Kong, F Campbell, A Kros - Nanoscale horizons, 2019 - pubs.rsc.org
To maximize drug targeting to solid tumors, cancer nanomedicines with prolonged
circulation times are required. To this end, poly (ethylene glycol)(PEG) has been widely …