A concise review on the synthesis and reactions of pyrazolopyrazine heterocycles
MA Abd ul‐Malik, RM Zaki… - Journal of …, 2018 - Wiley Online Library
The pyrazolopyrazine ring system is a very interesting class of heterocyclic compounds that
were considered as important scaffolds of many efficacious biologically active agents that …
were considered as important scaffolds of many efficacious biologically active agents that …
Microwave-assisted reactions in heterocyclic compounds with applications in medicinal and supramolecular chemistry
A Diaz-Ortiz, A Moreno… - … Chemistry & High …, 2007 - ingentaconnect.com
Microwave irradiation has been successfully applied in organic chemistry. Spectacular
accelerations, higher yields under milder reaction conditions and higher product purities …
accelerations, higher yields under milder reaction conditions and higher product purities …
[HTML][HTML] Ultrasound-assisted one-pot, three-component synthesis of spiro [indoline-3, 4′-pyrazolo [3, 4-b] pyridine]-2, 6′(1′ H)-diones in water
A simple, facile, efficient and three-component procedure for the synthesis of spiro [indoline-
3, 4′-pyrazolo [3, 4-b] pyridine]-2, 6′(1′ H)-diones by the reaction of 4-hydroxycumarin …
3, 4′-pyrazolo [3, 4-b] pyridine]-2, 6′(1′ H)-diones by the reaction of 4-hydroxycumarin …
Microwave irradiation in solvent-free conditions: an eco-friendly methodology to prepare indazoles, pyrazolopyridines and bipyrazoles by cycloaddition reactions
A study on the behaviour of vinylpyrazoles, pyrazolyl imines and pyrazolyl hydrazones as
dienes or dipoles is reported. Cycloaddition of the aforementioned compounds with electron …
dienes or dipoles is reported. Cycloaddition of the aforementioned compounds with electron …
Design, synthesis, antimicrobial, antiquorum-sensing and antitumor evaluation of new series of pyrazolopyridine derivatives
NS El-Gohary, MI Shaaban - European Journal of Medicinal Chemistry, 2018 - Elsevier
New series of pyrazolopyridines 1–15 were synthesized and esteemed for antimicrobial
effectiveness against S. aureus, B. cereus, E. coli, P. aeruginosa, C. albicans, A. fumigatus …
effectiveness against S. aureus, B. cereus, E. coli, P. aeruginosa, C. albicans, A. fumigatus …
Synthesis of pyrazolo [3, 4-b] pyridines by cycloaddition reactions under microwave irradiation
A Dı́az-Ortiz, JR Carrillo, FP Cossı́o… - Tetrahedron, 2000 - Elsevier
Microwave irradiation induces the cycloaddition of pyrazolylimines with aromatic and
aliphatic nitroalkenes to afford pyrazolo [3, 4-b] pyridines in 5–20min. Some of these …
aliphatic nitroalkenes to afford pyrazolo [3, 4-b] pyridines in 5–20min. Some of these …
Synthesis of spiro [benzopyrazolonaphthyridine-indoline]-diones and spiro [chromenopyrazolopyridine-indoline]-diones by one-pot, three-component methods in …
The synthesis of spiro [benzo [h] pyrazolo [3, 4-b][1, 6] naphthyridine-7, 3′-indoline]-2′, 6
(5H)-diones and spiro [chromeno [4, 3-b] pyrazolo [4, 3-e] pyridine-7, 3′-indoline]-2′, 6 …
(5H)-diones and spiro [chromeno [4, 3-b] pyrazolo [4, 3-e] pyridine-7, 3′-indoline]-2′, 6 …
[HTML][HTML] The biological activity of new thieno [2, 3-c] pyrazole compounds as anti-oxidants against toxicity of 4-nonylphenol in Clarias gariepinus
Synthesis of bi functionally substituted thieno [2, 3-c] pyrazole compounds was carried out
by a new method. The substituted group at position five is namely (carbonitrile …
by a new method. The substituted group at position five is namely (carbonitrile …
Synthesis of methyl 4-aryl-6-methyl-4, 7-dihydro-1 H-pyrazolo-[3, 4-b] pyridine-5-carboxylates from methyl 4-aryl-6-methyl-2-oxo-1, 2, 3, 4-tetrahydropyridine-5 …
Y Verdecia, M Suárez, A Morales… - Journal of the …, 1996 - pubs.rsc.org
Novel methyl 4, 7-dihydro-1H-pyrazolo [3, 4-b] pyridine-5-carboxylates 3a–e have been
prepared in a two step procedure from the readily available 2-oxo-1, 2, 3, 4 …
prepared in a two step procedure from the readily available 2-oxo-1, 2, 3, 4 …
Synthesis of some pyridothienopyrazolopyrimidopyrimidine and mercaptomethylpyrazolopyrimidine derivatives
AM Kamal El-Dean, AM Elkhawaga… - … , Sulfur, and Silicon, 2009 - Taylor & Francis
Mercaptomethylpyrazolopyrimidine (2) was synthesized and reacted with ethyl
chloroacetate to afford ethyl pyrazolpyrimidinylmethylmercapto acetate (3), which in turn was …
chloroacetate to afford ethyl pyrazolpyrimidinylmethylmercapto acetate (3), which in turn was …