The therapeutic potential of apigenin

B Salehi, A Venditti, M Sharifi-Rad, D Kręgiel… - International journal of …, 2019 - mdpi.com
Several plant bioactive compounds have exhibited functional activities that suggest they
could play a remarkable role in preventing a wide range of chronic diseases. The largest …

Phytochemicals as inhibitors of NF-κB for treatment of Alzheimer's disease

EJ Seo, N Fischer, T Efferth - Pharmacological research, 2018 - Elsevier
Alzheimer's disease (AD) is the most prevalent form of dementia. The exact pathophysiology
of this disease remains incompletely understood and safe and effective therapies are …

Baicalin mitigates cognitive impairment and protects neurons from microglia‐mediated neuroinflammation via suppressing NLRP 3 inflammasomes and TLR 4/NF‐κB …

X Jin, MY Liu, DF Zhang, X Zhong, K Du… - CNS Neuroscience …, 2019 - Wiley Online Library
Aims Baicalin (BAI), a flavonoid compound isolated from the root of Scutellaria baicalensis
Georgi, has been established to have potent anti‐inflammation and neuroprotective …

Neuropharmacological Review of the Nootropic Herb Bacopa monnieri

S Aguiar, T Borowski - Rejuvenation research, 2013 - liebertpub.com
This review synthesizes behavioral research with neuromolecular mechanisms putatively
involved with the low-toxicity cognitive enhancing action of Bacopa monnieri (BM), a …

Natural product-derived pharmacological modulators of Nrf2/ARE pathway for chronic diseases

H Kumar, IS Kim, SV More, BW Kim, DK Choi - Natural product reports, 2014 - pubs.rsc.org
Covering: 2000 to 2013 Oxidative stress is the central component of chronic diseases. The
nuclear factor erythroid 2-related factor 2/antioxidant response element (Nrf2/ARE) pathway …

Baicalin ameliorates cognitive impairment and protects microglia from LPS‐induced neuroinflammation via the SIRT1/HMGB1 pathway

Y Li, T Liu, Y Li, D Han, J Hong, N Yang… - Oxidative medicine …, 2020 - Wiley Online Library
Systemic inflammation often induces neuroinflammation and disrupts neural functions,
ultimately causing cognitive impairment. Furthermore, neuronal inflammation is the key …

[HTML][HTML] Herbal drugs and natural bioactive products as potential therapeutics: A review on pro-cognitives and brain boosters perspectives

S Halder, U Anand, S Nandy, P Oleksak, S Qusti… - Saudi Pharmaceutical …, 2021 - Elsevier
Memory, one of the most vital aspects of the human brain, is necessary for the effective
survival of an individual.'Memory'can be defined in various ways but in an overall view …

[HTML][HTML] Ginsenoside Rg1 alleviates Aβ deposition by inhibiting NADPH oxidase 2 activation in APP/PS1 mice

H Zhang, Y Su, Z Sun, M Chen, Y Han, Y Li… - Journal of ginseng …, 2021 - Elsevier
Abstract Background Ginsenoside Rg1 (Rg1), an active ingredient in ginseng, may be a
potential agent for the treatment of Alzheimer's disease (AD). However, the protective effect …

Toxin-induced experimental models of learning and memory impairment

SV More, H Kumar, DY Cho, YS Yun… - International journal of …, 2016 - mdpi.com
Animal models for learning and memory have significantly contributed to novel strategies for
drug development and hence are an imperative part in the assessment of therapeutics …

Gastrodin Protects Apoptotic Dopaminergic Neurons in a Toxin‐Induced Parkinson's Disease Model

H Kumar, IS Kim, SV More, BW Kim… - Evidence‐Based …, 2013 - Wiley Online Library
Gastrodia elata (GE) Blume is one of the most important traditional plants in Oriental
countries and has been used for centuries to improve various conditions. The phenolic …