Candida albicans is a major fungal pathogen of humans. It exists as a commensal in the oral
cavity, gut or genital tract of most individuals, constrained by the local microbiota, epithelial …

The insect immune response demonstrates many similarities to the innate immune response
of mammals and a wide range of insects is now employed to assess the virulence of …

The increasing occurrence of antibiotic-resistant bacteria and the dwindling antibiotic
research and development pipeline have created a pressing global health crisis. Here, we …

The insect immune response demonstrates a number of structural and functional similarities
to the innate immune system of mammals. As a result of these conserved features insects …

The release of extracellular vesicles (EV) by fungal organisms is considered an alternative
transport mechanism to trans‐cell wall passage of macromolecules. Previous studies have …

Insects are a highly successful group of animals that inhabit almost every habitat and
environment on Earth. Part of their success is due to a rapid and highly effective immune …

MCR-1 is a lipid A modifying enzyme that confers resistance to the antibiotic colistin. Here,
we analyse the impact of MCR-1 expression on E. coli morphology, fitness, competitiveness …

Conventional assays for quantifying the virulence of microbial pathogens and mutants have
traditionally relied upon the use of a range of mammalian species. A number of workers …

Invasive fungal infections are a leading cause of mortality among immunocompromised
individuals. Treatment is notoriously difficult with the limited armamentarium of antifungal …

Background Acinetobacter baumannii is an opportunistic pathogen that causes serious
nosocomial infection in intensive care units. In particular, carbapenem-resistant A …