[HTML][HTML] Hepatitis B virus PreS/S gene variants: pathobiology and clinical implications

T Pollicino, I Cacciola, F Saffioti, G Raimondo - Journal of hepatology, 2014 - Elsevier
The emergence and takeover of hepatitis B virus (HBV) variants carrying mutation (s) in the
preS/S genomic region is a fairly frequent event that may occur spontaneously or may be the …

[HTML][HTML] Genotypes and viral variants in chronic hepatitis B: A review of epidemiology and clinical relevance

CMN Croagh, PV Desmond, SJ Bell - World journal of hepatology, 2015 - ncbi.nlm.nih.gov
Abstract The Hepatitis B Virus (HBV) has a worldwide distribution and is endemic in many
populations. It is constantly evolving and 10 genotypic strains have been identified with …

Associations between hepatitis B virus mutations and the risk of hepatocellular carcinoma: a meta-analysis

S Liu, H Zhang, C Gu, J Yin, Y He… - Journal of the National …, 2009 - academic.oup.com
Background The association between hepatitis B virus (HBV) mutations and
hepatocarcinogenesis remains controversial because of conflicting data in the literature. We …

[PDF][PDF] Impact of hepatitis B virus (HBV) preS/S genomic variability on HBV surface antigen and HBV DNA serum levels

T Pollicino, G Amaddeo, A Restuccia, G Raffa… - …, 2012 - Wiley Online Library
To evaluate whether hepatitis B virus (HBV) preS/S gene variability has any impact on
serum hepatitis B surface antigen (HBsAg) levels and to analyze the replication capacity of …

[HTML][HTML] Clinical significance of hepatitis B surface antigen mutants

N Coppola, L Onorato, C Minichini… - World journal of …, 2015 - ncbi.nlm.nih.gov
Hepatitis B virus (HBV) infection is a major public health problem in many countries, with
nearly 300 million people worldwide carrying HBV chronic infection and over 1 million …

Association of hepatitis B virus pre-S deletions with the development of hepatocellular carcinoma in chronic hepatitis B

P Yeung, DKH Wong, CL Lai, J Fung… - Journal of Infectious …, 2011 - academic.oup.com
Background. We aimed to determine whether hepatitis B virus (HBV) pre-S deletion was an
independent factor for the development of hepatocellular carcinoma (HCC). Methods. Pre-S …

Hepatitis B virus pre-S deletion mutations are a risk factor for hepatocellular carcinoma: a matched nested case–control study

ZL Fang, CA Sabin, BQ Dong… - Journal of general …, 2008 - microbiologyresearch.org
A matched nested case–control study of 33 paired cases and controls was conducted,
based on a study cohort in Long An county, Guangxi, China, to determine whether infection …

[PDF][PDF] Current status of liver diseases in Korea: hepatitis B.

HB Chae, JH Kim, JK Kim, HJ Yim - 2009 - core.ac.uk
Hepatitis B virus (HBV) infection is the one of the most common causes of the liver diseases
in Korea. Since the discovery of Australia antigen (hepatitis associated antigen, or HBsAg …

[HTML][HTML] Hepatitis B virus genotypes and genome characteristics in China

HM Li, JQ Wang, R Wang, Q Zhao, L Li… - World journal of …, 2015 - ncbi.nlm.nih.gov
AIM: To analyze the hepatitis B virus (HBV) characters in China, as well as the correlation
between several HBV mutation and hepatitis symptoms. METHODS: A total of 1148 HBV …

Significant association of different preS mutations with hepatitis B-related cirrhosis or hepatocellular carcinoma

J Yin, J Xie, H Zhang, Q Shen, L Han, W Lu… - Journal of …, 2010 - Springer
Background The associations of nucleotide substitution mutations in the preS region of
hepatitis B virus (HBV) with hepatocellular carcinoma (HCC) and cirrhosis remain unknown …