In vitro microfluidic models for neurodegenerative disorders
Microfluidic devices enable novel means of emulating neurodegenerative disease
pathophysiology in vitro. These organ‐on‐a‐chip systems can potentially reduce animal …
pathophysiology in vitro. These organ‐on‐a‐chip systems can potentially reduce animal …
Compartmentalized microfluidic platforms: the unrivaled breakthrough of in vitro tools for neurobiological research
E Neto, L Leitão, DM Sousa, CJ Alves… - Journal of …, 2016 - Soc Neuroscience
Microfluidic technology has become a valuable tool to the scientific community, allowing
researchers to study fine cellular mechanisms with higher variable control compared with …
researchers to study fine cellular mechanisms with higher variable control compared with …
A single-cell atlas of human teeth
Teeth exert fundamental functions related to mastication and speech. Despite their great
biomedical importance, an overall picture of their cellular and molecular composition is still …
biomedical importance, an overall picture of their cellular and molecular composition is still …
Metabolomics studies of cell–cell interactions using single cell mass spectrometry combined with fluorescence microscopy
Cell–cell interactions are critical for transmitting signals among cells and maintaining their
normal functions from the single-cell level to tissues. In cancer studies, interactions between …
normal functions from the single-cell level to tissues. In cancer studies, interactions between …
A comparative in vitro study of the osteogenic and adipogenic potential of human dental pulp stem cells, gingival fibroblasts and foreskin fibroblasts
R Monterubbianesi, M Bencun, P Pagella… - Scientific reports, 2019 - nature.com
Human teeth contain a variety of mesenchymal stem cell populations that could be used for
cell-based regenerative therapies. However, the isolation and potential use of these cells in …
cell-based regenerative therapies. However, the isolation and potential use of these cells in …
Human dental pulp stem cells exhibit enhanced properties in comparison to human bone marrow stem cells on neurites outgrowth
Mesenchymal stem cells (MSCs) have the capacity to self‐renew and differentiate into
specific cell types and are, therefore, key players during tissue repair and regeneration. The …
specific cell types and are, therefore, key players during tissue repair and regeneration. The …
Stem cell-based approaches in dentistry
Repair of dental pulp and periodontal lesions remains a major clinical challenge. Classical
dental treatments require the use of specialised tissue-adapted materials with still …
dental treatments require the use of specialised tissue-adapted materials with still …
The effects of ageing on dental pulp stem cells, the tooth longevity elixir
I Iezzi, P Pagella, M Mattioli-Belmonte… - European Cells and …, 2019 - zora.uzh.ch
Stem cells are essential for tissue homeostasis and regeneration throughout the lifespan of
multicellular organisms. The decline in stem cell function during advanced age is associated …
multicellular organisms. The decline in stem cell function during advanced age is associated …
Pulp regeneration concepts for nonvital teeth: from tissue engineering to clinical approaches
V Orti, PY Collart-Dutilleul, S Piglionico… - … Engineering Part B …, 2018 - liebertpub.com
Following the basis of tissue engineering (Cells–Scaffold–Bioactive molecules),
regenerative endodontic has emerged as a new concept of dental treatment. Clinical …
regenerative endodontic has emerged as a new concept of dental treatment. Clinical …
Innovative dental stem cell‐based research approaches: the future of dentistry
S Miran, TA Mitsiadis, P Pagella - Stem Cells International, 2016 - Wiley Online Library
Over the past decade, the dental field has benefited from recent findings in stem cell biology
and tissue engineering that led to the elaboration of novel ideas and concepts for the …
and tissue engineering that led to the elaboration of novel ideas and concepts for the …