Glycan-mediated interactions are essential in many biological processes and regulate a
wide variety of cellular functions. However, characterizing these interactions is difficult …

This review is the eighth update of the original article published in 1999 on the application of
Matrix‐assisted laser desorption/ionization mass spectrometry (MALDI) mass spectrometry …

A judicious choice of photoreactive group is critical in successful photoaffinity labeling
studies of small molecule–protein interactions. A set of carbohydrate‐based photoaffinity …

Protein-carbohydrate binding depends on multivalent ligand display that is even more
important for low affinity carbohydrate–carbohydrate interactions. Detection and analysis of …

Photoaffinity labeling (PAL) has blossomed into a powerful and versatile tool for capture and
identification of biomolecular targets. However, low labeling efficiency for specific targets …

Antibody microarrays have important applications for the sensitive detection of biologically
important target molecules and as biosensors for clinical applications. Microarrays produced …

Multivalent carbohydrate photoaffinity probes were developed based on gold nanoparticles
(AuNPs) to provide a streamlined approach toward identification of carbohydrate-binding …

Diazirines are one of the most prominent functionalities in labeling experiments in vivo and
in vitro because they allow photochemical generation of carbenes. The strategy presented …

The use of photo-crosslinking glycoprobes represents a powerful strategy for the covalent
capture of labile protein complexes and allows detailed characterization of carbohydrate …

To identify sialic acid binding proteins from complex proteomes, three photocrosslinking
affinity-based probes were constructed using Neu5Ac (5 and 6) and Neu5Ac2en (7) …