Nanoparticles in the diagnosis and treatment of vascular aging and related diseases

H Xu, S Li, YS Liu - Signal Transduction and Targeted Therapy, 2022 - nature.com
Aging-induced alternations of vasculature structures, phenotypes, and functions are key in
the occurrence and development of vascular aging-related diseases. Multiple molecular and …

A review of the interaction among dietary antioxidants and reactive oxygen species

HE Seifried, DE Anderson, EI Fisher… - The Journal of nutritional …, 2007 - Elsevier
During normal cellular activities, various processes inside of cells produce reactive oxygen
species (ROS). Some of the most common ROS are hydrogen peroxide (H2O2), superoxide …

Role of G-protein-coupled adenosine receptors in downregulation of inflammation and protection from tissue damage

A Ohta, M Sitkovsky - Nature, 2001 - nature.com
Inappropriate or prolonged inflammation is the main cause of many diseases; for this reason
it is important to understand the physiological mechanisms that terminate inflammation in …

Circulating IL-6 and CRP are associated with MRI findings in the elderly: the 3C-Dijon Study

CL Satizabal, YC Zhu, B Mazoyer, C Dufouil… - Neurology, 2012 - AAN Enterprises
Objective: The relation between inflammation and brain MRI findings in the elderly remains
poorly known. We investigated the association of circulating interleukin-6 (IL-6) and C …

An update on bioactive plant lignans

M Saleem, HJ Kim, MS Ali, YS Lee - Natural product reports, 2005 - pubs.rsc.org
Covering: 2000 to 2004 Lignans are a class of secondary plant metabolites produced by
oxidative dimerization of two phenylpropanoid units. Although their molecular backbone …

Circulating anthocyanin metabolites mediate vascular benefits of blueberries: insights from randomized controlled trials, metabolomics, and nutrigenomics

A Rodriguez-Mateos, G Istas, L Boschek… - The Journals of …, 2019 - academic.oup.com
Potential health benefits of blueberries may be due to vascular effects of anthocyanins that
predominantly circulate in blood as phenolic acid metabolites. We investigated which role …

Interleukin-6 and C-reactive protein as predictors of cognitive decline in late midlife

A Singh-Manoux, A Dugravot, E Brunner, M Kumari… - Neurology, 2014 - AAN Enterprises
Objective: Peripheral inflammatory markers are elevated in patients with dementia. In order
to assess their etiologic role, we examined whether interleukin-6 (IL-6) and C-reactive …

Role of cytokines in cardiovascular diseases: a focus on endothelial responses to inflammation

S Kofler, T Nickel, M Weis - Clinical science, 2005 - portlandpress.com
Complex cellular and inflammatory interactions are involved in the progress of vascular
diseases. Endothelial cells, upon exposure to cytokines, undergo profound alterations of …

Cerebral vasospasm after subarachnoid hemorrhage: putative role of inflammation

AS Dumont, RJ Dumont, MM Chow, C Lin… - …, 2003 - journals.lww.com
Abstract CEREBRAL VASOSPASM IS a common, formidable, and potentially devastating
complication in patients who have sustained subarachnoid hemorrhage (SAH). Despite …

Melatonin prevents methotrexate‐induced hepatorenal oxidative injury in rats

N Jahovic, H Çevik, AÖ Şehirli… - Journal of pineal …, 2003 - Wiley Online Library
Regarding the mechanisms of methotrexate (MTX) hepatotoxicity and nephrotoxicity, several
hypotheses have been put forward, among which oxidative stress (including depletion of …