Since the first description of the association between chronic kidney disease and heart
disease, many epidemiological studies have confirmed and extended this finding. As …

Objective To qualitatively and quantitatively investigate the link between a low estimated
glomerular filtration rate (eGFR) at baseline and risk of future stroke. Design Systematic …

Importance The established chronic kidney disease (CKD) progression end point of end-
stage renal disease (ESRD) or a doubling of serum creatinine concentration (corresponding …

Kidney function predicts cardiovascular and all-cause mortality, but little is known about the
association of changes in estimated GFR (eGFR) with clinical outcomes. We investigated …

Genome-wide association studies (GWASs) have identified multiple loci associated with
cross-sectional eGFR, but a systematic genetic analysis of kidney function decline over time …

Using a community-based cohort we studied the association between changes in the
estimated glomerular filtration rate (eGFR) over time and the risk of all-cause mortality. We …

Limited follow-up studies are available as to whether special job-types, such as day-night
rotating shift work, contribute to the progression of metabolic syndrome among female …

Abstract eGFR is a robust predictor of ESRD risk. However, the prognostic information
gained from the past trajectory (slope) beyond that of the current eGFR is unclear. We …

Chronic non-communicable diseases (NCD) that manifest primarily later in life, such as
cancer, cardiovascular disease, diabetes and chronic obstructive pulmonary disease …

Background Kidney impairment is noted in primary aldosteronism (PA), and probably
initiated by glomerular hyperfiltration. Methods A prospectively defined survey was …