Sphingolipids are a specialized group of lipids essential to the composition of the plasma
membrane of many cell types; however, they are primarily localized within the nervous …

UDP-glycosyltransferases (UGTs) catalyze the covalent addition of sugars to a broad range
of lipophilic molecules. This biotransformation plays a critical role in elimination of a broad …

Renal nitrogen metabolism primarily involves urea and ammonia metabolism, and is
essential to normal health. Urea is the largest circulating pool of nitrogen, excluding nitrogen …

Dietary protein intake is linked to an increased incidence of type 2 diabetes (T2D). Although
dietary protein dilution (DPD) can slow the progression of some aging-related disorders …

Acid-base homeostasis is critical to maintenance of normal health. Renal ammonia
excretion is the quantitatively predominant component of renal net acid excretion, both …

Kidneys are central in the regulation of multiple physiological functions, such as removal of
metabolic wastes and toxins, maintenance of electrolyte and fluid balance, and control of pH …

Diabetic nephropathy (DN) is a major life-threatening complication of diabetes. Renal
lesions affect glomeruli and tubules, but the pathogenesis is not completely understood …

For many years, traditional histology has been the gold standard for the diagnosis of many
diseases. However, alternative and powerful techniques have appeared in recent years that …

This review is an effort towards the development of substrate reduction therapy using
cerebroside sulfotransferase (CST) as a target protein for the development of inhibitors …

This review is the eighth update of the original article published in 1999 on the application of
Matrix‐assisted laser desorption/ionization mass spectrometry (MALDI) mass spectrometry …