Platelets are chief cells in hemostasis. Apart from their hemostatic roles, platelets are major
inflammatory effector cells that can influence both innate and adaptive immune responses …

Platelets are inflammatory anuclear cells with a well-established role in the development
and manifestation of atherosclerosis. Activated platelets secrete a plethora of chemokines …

Nearly one trillion platelets circulate in the blood to monitor and preserve the integrity of the
vasculature. However, haemostasis is not their only function. Platelets are also potent …

Introduction Cell stimulation leads to the shedding of phosphatidylserine (PS)-rich
microparticles (MPs). Because autoimmune diseases (AIDs) are characterized by cell …

Extracellular vesicles (EVs) are small membrane‐bound vesicles released by cells under
various conditions. They are found in the extracellular milieu in all biological fluids. As the …

Extracellular vesicles (EVs) consist of exosomes released upon fusion of multivesicular
bodies with the cell plasma membrane and microparticles shed directly from the cell …

Objectives Neutrophil extracellular traps (NETs) act in various rheumatic diseases. Although
NET formation was originally described as a nicotinamide adenine dinucleotide phosphate …

Patients with rheumatoid arthritis (RA) are at high risk of cardiovascular events. Platelet
biomarkers are involved in inflammation, atherosclerosis and thrombosis. Cardiovascular …

Abstract The CD40-CD40L system is a pathway which is associated with both prothrombotic
and proinflammatory effects. CD40 and its ligand were first discovered on the surface of …

Vascular injury is the initial manifestation of inflammation resulting in the recruitment and
activation of various cell types. The integrity of the vascular wall is monitored by platelets that …