Placental origins of chronic disease
Epidemiological evidence links an individual's susceptibility to chronic disease in adult life to
events during their intrauterine phase of development. Biologically this should not be …
events during their intrauterine phase of development. Biologically this should not be …
Sex-specific placental responses in fetal development
CS Rosenfeld - Endocrinology, 2015 - academic.oup.com
The placenta is an ephemeral but critical organ for the survival of all eutherian mammals
and marsupials. It is the primary messenger system between the mother and fetus, where …
and marsupials. It is the primary messenger system between the mother and fetus, where …
The placenta harbors a unique microbiome
Humans and their microbiomes have coevolved as a physiologic community composed of
distinct body site niches with metabolic and antigenic diversity. The placental microbiome …
distinct body site niches with metabolic and antigenic diversity. The placental microbiome …
Integrative single-cell and cell-free plasma RNA transcriptomics elucidates placental cellular dynamics
The human placenta is a dynamic and heterogeneous organ critical in the establishment of
the fetomaternal interface and the maintenance of gestational well-being. It is also the major …
the fetomaternal interface and the maintenance of gestational well-being. It is also the major …
The human neonatal gut microbiome: a brief review
EC Gritz, V Bhandari - Frontiers in pediatrics, 2015 - frontiersin.org
The field of genomics has expanded into subspecialties such as metagenomics over the
course of the last decade and a half. The development of massively parallel sequencing …
course of the last decade and a half. The development of massively parallel sequencing …
Developmental origins of health and disease: brief history of the approach and current focus on epigenetic mechanisms
PD Wadhwa, C Buss, S Entringer… - Seminars in …, 2009 - thieme-connect.com
ABSTRACT “Barker's hypothesis” emerged almost 25 years ago from epidemiological
studies of birth and death records that revealed a high geographic correlation between rates …
studies of birth and death records that revealed a high geographic correlation between rates …
Sex and the human placenta: mediating differential strategies of fetal growth and survival
VL Clifton - Placenta, 2010 - Elsevier
There are known sex specific differences in fetal and neonatal morbidity and mortality. There
are also known differences in birthweight centile with males generally being larger than …
are also known differences in birthweight centile with males generally being larger than …
[HTML][HTML] Placental origins of adverse pregnancy outcomes: potential molecular targets: an Executive Workshop Summary of the Eunice Kennedy Shriver National …
JV Ilekis, E Tsilou, S Fisher, VM Abrahams… - American journal of …, 2016 - Elsevier
Although much progress is being made in understanding the molecular pathways in the
placenta that are involved in the pathophysiology of pregnancy-related disorders, a …
placenta that are involved in the pathophysiology of pregnancy-related disorders, a …
The placenta as a mediator of stress effects on neurodevelopmental reprogramming
SL Bronson, TL Bale - Neuropsychopharmacology, 2016 - nature.com
Adversity experienced during gestation is a predictor of lifetime neuropsychiatric disease
susceptibility. Specifically, maternal stress during pregnancy predisposes offspring to sex …
susceptibility. Specifically, maternal stress during pregnancy predisposes offspring to sex …
Prenatal stress-induced increases in placental inflammation and offspring hyperactivity are male-specific and ameliorated by maternal antiinflammatory treatment
SL Bronson, TL Bale - Endocrinology, 2014 - academic.oup.com
Adverse experiences during gestation such as maternal stress and infection are known risk
factors for neurodevelopmental disorders, including schizophrenia, autism, and attention …
factors for neurodevelopmental disorders, including schizophrenia, autism, and attention …