Metabolic and cardiovascular adverse effects associated with antipsychotic drugs

M De Hert, J Detraux, R Van Winkel, W Yu… - Nature Reviews …, 2012 - nature.com
Antipsychotic medications can induce cardiovascular and metabolic abnormalities (such as
obesity, hyperglycemia, dyslipidemia and the metabolic syndrome) that are associated with …

Metabolic and endocrine adverse effects of second-generation antipsychotics in children and adolescents: a systematic review of randomized, placebo controlled …

M De Hert, M Dobbelaere, EM Sheridan… - European …, 2011 - cambridge.org
Second-generation antipsychotics (SGA) are being used more often than ever before in
children and adolescents with psychotic and a wide range of non-psychotic disorders …

20‐year follow‐up study of physical morbidity and mortality in relationship to antipsychotic treatment in a nationwide cohort of 62,250 patients with schizophrenia …

H Taipale, A Tanskanen, J Mehtälä… - World …, 2020 - Wiley Online Library
Antipsychotics are effective in preventing relapses of schizophrenia, but it is generally
believed that their long‐term use is harmful for patients' physical well‐being. However, there …

Premature mortality among adults with schizophrenia in the United States

M Olfson, T Gerhard, C Huang, S Crystal… - JAMA …, 2015 - jamanetwork.com
Importance Although adults with schizophrenia have a significantly increased risk of
premature mortality, sample size limitations of previous research have hindered the …

[HTML][HTML] Physical illness in patients with severe mental disorders. I. Prevalence, impact of medications and disparities in health care

M De Hert, CU Correll, J Bobes… - World …, 2011 - ncbi.nlm.nih.gov
The lifespan of people with severe mental illness (SMI) is shorter compared to the general
population. This excess mortality is mainly due to physical illness. We report prevalence …

Evidence-based guidelines for the pharmacological treatment of schizophrenia: recommendations from the British Association for Psychopharmacology

TRE Barnes… - Journal of …, 2011 - journals.sagepub.com
These guidelines from the British Association for Psychopharmacology address the scope
and targets of pharmacological treatment for schizophrenia. A consensus meeting, involving …

Guideline concordant monitoring of metabolic risk in people treated with antipsychotic medication: systematic review and meta-analysis of screening practices

AJ Mitchell, V Delaffon, D Vancampfort… - Psychological …, 2012 - cambridge.org
BackgroundDespite increased cardiometabolic risk in individuals with mental illness taking
antipsychotic medication, metabolic screening practices are often incomplete or …

Weight gain and metabolic risks associated with antipsychotic medications in children and adolescents

L Maayan, CU Correll - Journal of child and adolescent …, 2011 - liebertpub.com
Background: Antipsychotic-related weight gain and metabolic adverse effects have become
a major focus, especially in youth. Methods: Review of randomized, cohort, and …

Past and present progress in the pharmacologic treatment of schizophrenia

JM Kane, CU Correll - The Journal of clinical psychiatry, 2010 - psychiatrist.com
Despite treatment advances over the past decades, schizophrenia remains one of the most
severe psychiatric disorders that is associated with a chronic relapsing course and marked …

From receptor pharmacology to improved outcomes: individualising the selection, dosing, and switching of antipsychotics

CU Correll - European Psychiatry, 2010 - cambridge.org
Determinants of antipsychotic selection and response include parameters of the primary
disorder, psychiatric and physical comorbidities, past treatment effects, patient preferences …