Polycystic ovary syndrome

AE Joham, RJ Norman, E Stener-Victorin… - The lancet Diabetes & …, 2022 - thelancet.com
Polycystic ovary syndrome (PCOS) affects 5–18% of women, and is a reproductive,
metabolic, and psychological condition with impacts across the lifespan. The cause is …

[HTML][HTML] Metabolic dysfunction in polycystic ovary syndrome: Pathogenic role of androgen excess and potential therapeutic strategies

MA Sanchez-Garrido, M Tena-Sempere - Molecular metabolism, 2020 - Elsevier
Background Polycystic ovary syndrome (PCOS) is the most common endocrinopathy among
reproductive age women. Although its cardinal manifestations include hyperandrogenism …

Epigenetic inheritance of polycystic ovary syndrome—challenges and opportunities for treatment

E Stener-Victorin, Q Deng - Nature Reviews Endocrinology, 2021 - nature.com
Polycystic ovary syndrome (PCOS) is the main cause of female infertility worldwide and is
associated with a substantially increased lifetime risk of comorbidities, including type 2 …

Genetic basis of polycystic ovary syndrome (PCOS): current perspectives

MJ Khan, A Ullah, S Basit - The application of clinical genetics, 2019 - Taylor & Francis
Polycystic ovary syndrome (PCOS) is a common infertility disorder affecting a significant
proportion of the global population. It is the main cause of anovulatory infertility in women …

Insulin resistance in polycystic ovary syndrome: a systematic review and meta-analysis of euglycaemic–hyperinsulinaemic clamp studies

S Cassar, ML Misso, WG Hopkins, CS Shaw… - Human …, 2016 - academic.oup.com
STUDY QUESTION What is the degree of intrinsic insulin resistance (IR) in women with
polycystic ovary syndrome (PCOS) and the relative contribution of BMI to overall IR based …

Impaired glucose tolerance, type 2 diabetes and metabolic syndrome in polycystic ovary syndrome: a systematic review and meta-analysis

LJ Moran, ML Misso, RA Wild… - Human reproduction …, 2010 - academic.oup.com
BACKGROUND Polycystic ovary syndrome (PCOS) is a common condition in reproductive-
aged women associated with impaired glucose tolerance (IGT), type 2 diabetes mellitus …

Insulin and hyperandrogenism in women with polycystic ovary syndrome

CG Baptiste, MC Battista, A Trottier… - The Journal of steroid …, 2010 - Elsevier
Polycystic ovary syndrome (PCOS) is a very common endocrine disorder characterized by
chronic anovulation, clinical and/or biochemical hyperandrogenism, and/or polycystic …

Hyperandrogenism accompanies increased intra-abdominal fat storage in normal weight polycystic ovary syndrome women

DA Dumesic, AL Akopians, VK Madrigal… - The Journal of …, 2016 - academic.oup.com
Context: Normal weight polycystic ovary syndrome (PCOS) women may have altered
adipose structure-function underlying metabolic dysfunction. Objective: This study examines …

Metformin for the treatment of the polycystic ovary syndrome

JE Nestler - New England Journal of Medicine, 2008 - Mass Medical Soc
A 23-year-old woman with the polycystic ovary syndrome presents for evaluation and
possible treatment. She has a family history of diabetes, is obese, and has impaired glucose …

Meta-analysis of cardiovascular disease risk markers in women with polycystic ovary syndrome

KA Toulis, DG Goulis, G Mintziori… - Human reproduction …, 2011 - academic.oup.com
BACKGROUND The relation between polycystic ovary syndrome (PCOS) and
cardiovascular disease (CVD) remains unclear. In an attempt to provide high-quality …