The progress in understanding and treatment of diabetic retinopathy

AW Stitt, TM Curtis, M Chen, RJ Medina… - Progress in retinal and …, 2016 - Elsevier
Diabetic retinopathy is the most frequently occurring complication of diabetes mellitus and
remains a leading cause of vision loss globally. Its aetiology and pathology have been …

Epigenetic mechanisms in diabetic complications and metabolic memory

MA Reddy, E Zhang, R Natarajan - Diabetologia, 2015 - Springer
The incidence of diabetes and its associated micro-and macrovascular complications is
greatly increasing worldwide. The most prevalent vascular complications of both type 1 and …

[HTML][HTML] Oxidative stress, mitochondrial damage and diabetic retinopathy

RA Kowluru, M Mishra - Biochimica et Biophysica Acta (BBA)-Molecular …, 2015 - Elsevier
Diabetes has emerged as an epidemic of the 21st century, and retinopathy remains the
leading cause of blindness in young adults and the mechanism of this blinding disease …

Oxidative stress and epigenetic modifications in the pathogenesis of diabetic retinopathy

RA Kowluru, A Kowluru, M Mishra, B Kumar - Progress in retinal and eye …, 2015 - Elsevier
Diabetic retinopathy remains the major cause of blindness among working age adults.
Although a number of metabolic abnormalities have been associated with its development …

Imaging and biomarkers in diabetic macular edema and diabetic retinopathy

CC Kwan, AA Fawzi - Current diabetes reports, 2019 - Springer
Abstract Purpose of Review Diabetic retinopathy (DR) is the leading cause of acquired
vision loss in adults across the globe. Early identification and treatment of patients with DR is …

[HTML][HTML] Diabetes and retinal vascular dysfunction

ES Shin, CM Sorenson, N Sheibani - Journal of ophthalmic & …, 2014 - ncbi.nlm.nih.gov
Diabetes predominantly affects the microvascular circulation of the retina resulting in a
range of structural changes unique to this tissue. These changes ultimately lead to altered …

Evaluating the role of epigenetic histone modifications in the metabolic memory of type 1 diabetes

F Miao, Z Chen, S Genuth, A Paterson, L Zhang… - Diabetes, 2014 - Am Diabetes Assoc
We assessed whether epigenetic histone posttranslational modifications are associated with
the prolonged beneficial effects (metabolic memory) of intensive versus conventional …

Proteomic biomarkers of retinal inflammation in diabetic retinopathy

H Youngblood, R Robinson, A Sharma… - International journal of …, 2019 - mdpi.com
Diabetic retinopathy (DR), a sight-threatening neurovasculopathy, is the leading cause of
irreversible blindness in the developed world. DR arises as the result of prolonged …

Advances in our understanding of diabetic retinopathy

AW Stitt, N Lois, RJ Medina, P Adamson… - Clinical …, 2013 - portlandpress.com
Diabetic retinopathy remains the most common complication of diabetes mellitus and is a
leading cause of visual loss in industrialized nations. The clinicopathology of the diabetic …

New highlights of resveratrol: A review of properties against ocular diseases

D Delmas, C Cornebise, F Courtaut, J Xiao… - International Journal of …, 2021 - mdpi.com
Eye diseases are currently a major public health concern due to the growing number of
cases resulting from both an aging of populations and exogenous factors linked to our …