Stroke is one of the leading causes for disability worldwide. Motor function deficits due to
stroke affect the patients' mobility, their limitation in daily life activities, their participation in …

Depression, the most frequent psychiatric disorder following ischaemic stroke, negatively
affects survivals' functional outcome, response to rehabilitation and quality of life …

Poststroke depression (PSD) is common, affecting approximately one third of stroke
survivors at any one time after stroke. Individuals with PSD are at a higher risk for suboptimal …

Background Trials of fluoxetine for recovery after stroke report conflicting results. The
Assessment oF FluoxetINe In sTroke recoverY (AFFINITY) trial aimed to show if daily oral …

Background Hemiplegia and hemiparesis are the most common deficits caused by stroke. A
few small clinical trials suggest that fluoxetine enhances motor recovery but its clinical …

Neurotrophic factors, particularly brain-derived neurotrophic factor (BDNF) and other
members of the neurotrophin family, are central mediators of the activity-dependent plasticity …

Background Stroke is the major cause of adult disability. Selective serotonin reuptake
inhibitors (SSRIs) have been used for many years to manage depression. Recently, small …

The interaction between depression and stroke is highly complex. Post‐stroke depression
(PSD) is among the most frequent neuropsychiatric consequences of stroke. Depression …

Major depressive disorder is the most common mental disorder with significant economic
burden and limited treatments. Acupuncture has emerged as a promising non …

Brain-derived neurotrophic factor (BDNF) is a secreted protein that has been linked to
numerous aspects of plasticity in the central nervous system (CNS). Stress-induced …