The perception that intracellular lipolysis is a straightforward process that releases fatty
acids from fat stores in adipose tissue to generate energy has experienced major revisions …

Lipids entering the gastrointestinal tract include dietary lipids (triacylglycerols, cholesteryl
esters and phospholipids) and endogenous lipids from bile (phospholipids and cholesterol) …

Atherosclerosis is the underlying cause of heart attack and stroke. Early observations that
cholesterol is a key component of arterial plaques gave rise to the cholesterol hypothesis for …

Nonalcoholic fatty liver disease (NAFLD) is an increasing global public health burden.
NAFLD is strongly associated with type 2 diabetes mellitus, obesity and cardiovascular …

Triglycerides are exclusively transported with chylomicrons and this process is critically
dependent on MTP. In addition to chylomicrons, absorption of phospholipids, free …

Mammalian carboxylesterases hydrolyze a wide range of xenobiotic and endogenous
compounds, including lipid esters. Physiological functions of carboxylesterases in lipid …

Hepatitis C virus, a major human pathogen, produces infectious virus particles with several
unique features, such as an ability to interact with serum lipoproteins, a dizzyingly …

The esterification of a fatty acyl moiety to diacylglycerol to form triacylglycerol (TAG) is
catalysed by two diacylglycerol O-acyltransferases (DGATs) encoded by genes belonging to …

Research into lipoprotein metabolism has developed because understanding lipoprotein
metabolism has important clinical indications. Lipoproteins are risk factors for cardiovascular …

The oral bioavailability of lipophilic bioactive molecules can be greatly increased by
encapsulating them within engineered lipid nanoparticles (ELNs), such as micelles …