Hepatitis B protein x (HBx) has been reported to promote tumorigenesis in hepatitis B virus
(HBV)-related hepatocellular carcinoma (HCC), but the mechanism awaits further …

MicroRNAs (miRNAs) are a group of small, single-stranded, non-coding RNAs
approximately 22 nucleotides in length. The dysregulation of miRNAs has been widely …

Cold stimulation dynamically remodels mitochondria in brown adipose tissue (BAT) to
facilitate non-shivering thermogenesis in mammals, but what regulates mitochondrial …

Dysregulated glycolysis has been noted in several pathological processes characterized by
supporting cell proliferation. Nonetheless, the role of glycolysis reprogramming is not well …

Simple Summary Cardiovascular diseases are the leading cause of death. Obesity has been
associated with multiple pathologic cardiovascular-related conditions. Epicardial adipose …

The study of mitochondria-targeted antitumor treatment has been extensively developed as
target sites to improve the efficiency of cancer therapy. On this basis, cellulose nanocrystal …

Translation of upstream open reading frames (uORFs) typically abrogates translation of
main (m) ORFs. The molecular mechanism of uORF regulation in cells is not well …

Cardiac pathological remodeling, a primary contributor to heart failure (HF) and death, is an
important target for HF therapy. However, the signaling pathways that govern cardiac …

Aims Mitochondria play a vital role in cellular metabolism and energetics and support
normal cardiac function. Disrupted mitochondrial function and homeostasis cause a variety …

Causes and treatments for heart failure (HF) have been investigated for over a century
culminating in data that have led to numerous pharmacological and surgical therapies …