This article summarizes anatomical, neurophysiological, pharmacological, and brain
imaging studies in humans and animals that have provided insights into the neural circuitry …

From time to time we publish a full review of drugs that are available for the treatment of
common conditions. In this issue, the review is written by two of the leading authorities in the …

The pharmacological treatment of urinary incontinence Page 1 BJU International (1999), 84,
923–947 REVIEW The pharmacological treatment of urinary incontinence K.-E …

Functions of the lower urinary tract to store and periodically eliminate urine are regulated by
a complex neural control system in the brain, spinal cord, and peripheral autonomic ganglia …

Purinergic signalling is involved in a number of physiological and pathophysiological
activities in the lower urinary tract. In the bladder of laboratory animals there is …

Non-neuronal release of acetylcholine (ACh) has been proposed to play a role in urinary
bladder function. These studies investigated the expression and function of the non …

Objectives To conduct a systematic review to determine whether there is an association
between metabolic syndrome (MetS) and lower urinary tract symptoms (LUTS) or overactive …

Background Urinary incontinence (UI) is a common geriatric syndrome associated with
physical and cognitive impairments. The association between type of UI and sedentary …

CONTEXT: Urgency is the core symptom of the overactive bladder symptom complex, but
the underlying mechanisms are not fully understood. OBJECTIVE: To review clinical and …

Aims Dysregulation of bladder afferent activity and detrusor smooth muscle behavior leads
to a constellation of lower urinary tract symptoms (LUTS), which includes overactive bladder …