The application of nanoparticles in immunotherapy for hepatocellular carcinoma

X Hu, H Zhu, X He, J Chen, L Xiong, Y Shen, J Li… - Journal of Controlled …, 2023 - Elsevier
Hepatocellular carcinoma (HCC) remains one of the leading causes of cancer-related
deaths worldwide, however, current clinical diagnostic and treatment approaches remain …

Immunogenic cell death-related risk signature predicts prognosis and characterizes the tumour microenvironment in lower-grade glioma

J Cai, Y Hu, Z Ye, L Ye, L Gao, Y Wang, Q Sun… - Frontiers in …, 2022 - frontiersin.org
Lower-grade glioma (LGG) is a common malignant primary tumour in the central nervous
system, and most patients eventually develop highly aggressive gliomas despite …

Glioblastoma microenvironment—from biology to therapy

ZM Tapp, P Rajappa… - Genes & …, 2024 - genesdev.cshlp.org
Glioblastoma (GBM) is the most aggressive primary brain cancer. These tumors exhibit high
intertumoral and intratumoral heterogeneity in neoplastic and nonneoplastic compartments …

[HTML][HTML] Identifies microtubule-binding protein CSPP1 as a novel cancer biomarker associated with ferroptosis and tumor microenvironment

W Wang, J Zhang, Y Wang, Y Xu, S Zhang - Computational and Structural …, 2022 - Elsevier
Centrosome and spindle pole-associated protein (CSPP1) is a centrosome and microtubule-
binding protein that plays a role in cell cycle-dependent cytoskeleton organization and cilia …

The hypoxia‐related gene COL5A1 is a prognostic and immunological biomarker for multiple human tumors

H Zhu, X Hu, S Feng, Z Jian, X Xu… - … Medicine and Cellular …, 2022 - Wiley Online Library
Background. Collagen type V alpha 1 chain (COL5A1) is a hypoxia‐related gene (a
collagen family protein) and participates in the formation of the extracellular matrix. Although …

TUBA1C is a potential new prognostic biomarker and promotes bladder urothelial carcinoma progression by regulating the cell cycle

Y Jiang, C Zhu, H Huang, G Huang, B Fu, X Xi - BMC cancer, 2023 - Springer
Background TUBA1C is an α-tubulin isoform involved in mitosis, and its dysregulation has
been implicated in tumor progression. There is still no clear understanding of its role in …

Predictive value of PIMREG in the prognosis and response to immune checkpoint blockade of glioma patients

H Zhu, X Hu, S Feng, L Gu, Z Jian, N Zou… - Frontiers in …, 2022 - frontiersin.org
Glioma is the most common primary brain tumor in the human brain. The present study was
designed to explore the expression of PIMREG in glioma and its relevance to the …

The oncogenic role of tubulin alpha-1c chain in human tumours

X Hu, H Zhu, B Chen, X He, Y Shen, X Zhang, Y Xu… - BMC cancer, 2022 - Springer
Tubulin alpha-1c chain (TUBA1C), a subtype of α-tubulin, has been shown to be involved in
cell proliferation and cell cycle progression in several cancers and to influence cancer …

Transmembrane and coiled-coil domains 3 is a diagnostic biomarker for predicting immune checkpoint blockade efficacy in hepatocellular carcinoma

X Hu, H Zhu, S Feng, C Wang, Y Ye, X Xiong - Frontiers in Genetics, 2022 - frontiersin.org
Liver hepatocellular carcinoma (LIHC) is a malignancy with a high mortality and morbidity
rate worldwide. However, the pathogenesis of LIHC has still not been thoroughly studied …

The tubulin code and tubulin-modifying enzymes in autophagy and cancer

D Trisciuoglio, F Degrassi - Cancers, 2021 - mdpi.com
Simple Summary Microtubules are tubulin polymers that constitute the structure of eukaryotic
cells. They control different cell functions that are often deregulated in cancer, such as cell …