Preclinical models of medication-related osteonecrosis of the jaw (MRONJ)
JI Aguirre, EJ Castillo, DB Kimmel - Bone, 2021 - Elsevier
Medication-related osteonecrosis of the jaw (MRONJ) is a potentially severe adverse event
affecting patients with cancer and patients with osteoporosis who have been treated with …
affecting patients with cancer and patients with osteoporosis who have been treated with …
Medication-Related Osteonecrosis: Why the Jawbone?
S Kuehn, R Scariot, M Elsalanty - Dentistry Journal, 2023 - mdpi.com
Medication-related osteonecrosis of the jaw (MRONJ) has emerged as a complication of anti-
resorptive medications. Despite its low incidence rate, this problem has gained attention in …
resorptive medications. Despite its low incidence rate, this problem has gained attention in …
Rodents as an animal model for studying tooth extraction-related medication-related osteonecrosis of the jaw: assessment of outcomes
Objective To assess the outcomes of several rodent animal models for studying tooth
extraction-related medication-related osteonecrosis of the jaw (MRONJ). Design After a …
extraction-related medication-related osteonecrosis of the jaw (MRONJ). Design After a …
[HTML][HTML] The effect of drug holiday on preventing medication-related osteonecrosis of the jaw in osteoporotic rat model
Background Medication-related osteonecrosis of the jaw (MRONJ) is a severe complication
associated with antiresorptive medications managing osteoporosis, such as …
associated with antiresorptive medications managing osteoporosis, such as …
Medication‐related osteonecrosis of the jaw‐like lesions in rodents: a comprehensive systematic review and meta‐analysis
S Kuroshima, M Sasaki, H Murata, T Sawase - Gerodontology, 2019 - Wiley Online Library
Objective The aim of this comprehensive systematic review and meta‐analysis was to
investigate the pathology and pathogenesis of medication‐related osteonecrosis of the jaw …
investigate the pathology and pathogenesis of medication‐related osteonecrosis of the jaw …
Introducing a protocol to create bisphosphonate-related osteonecrosis of the jaw in rat animal model
Objective Previously published animal investigations on bisphosphonate-related
osteonecrosis of the jaws (BRONJ) showed a variety of methods for BRONJ induction and …
osteonecrosis of the jaws (BRONJ) showed a variety of methods for BRONJ induction and …
Antiresorptive-type and discontinuation-timing affect ONJ burden
D Hadaya, A Soundia, I Gkouveris… - Journal of Dental …, 2021 - journals.sagepub.com
Osteonecrosis of the jaws (ONJ), a severe side effect of antiresorptive medications, is
characterized by exposed, nonhealing bone in the oral cavity. Treatment options for ONJ …
characterized by exposed, nonhealing bone in the oral cavity. Treatment options for ONJ …
Effects of pre-extraction intermittent PTH administration on extraction socket healing in bisphosphonate administered ovariectomized rats
JY Kim, HW Jang, JI Kim, IH Cha - Scientific reports, 2021 - nature.com
The purpose of this study was to investigate the effect of administering intermittent
parathyroid hormone (iPTH) before tooth extraction versus after tooth extraction on the risk of …
parathyroid hormone (iPTH) before tooth extraction versus after tooth extraction on the risk of …
The starting point for bisphosphonate-related osteonecrosis of the jaw: Alveolar bone or oral mucosa? A randomized, controlled experimental study
Objective Although over a decade has passed since first introduction of BRONJ, the exact
pathophysiology of this disease is still unclear. The present experimental study aimed to …
pathophysiology of this disease is still unclear. The present experimental study aimed to …
Free flap reconstruction for patients with bisphosphonate related osteonecrosis of the jaws after mandibulectomy
T Mücke, M Jung, S Koerdt, DA Mitchell… - Journal of Cranio …, 2016 - Elsevier
Introduction Bisphosphonate related osteonecrosis of the jaws (BRONJ) is a recognised
unwanted effect of these drugs which affect bone remodelling. Treatment options range from …
unwanted effect of these drugs which affect bone remodelling. Treatment options range from …