Biopharmaceutics Classification System (BCS) Class II and IV drugs suffer from poor
aqueous solubility and hence low bioavailability. Most of these drugs are hydrophobic and …

Cocrystals have gained much interest in recent years owing to their potential to improve the
physicochemical properties of the parent compounds. It was once thought that cocrystals …

Introduction: Cocrystallization is an effective crystal engineering approach for modifying the
crystal structure and properties of drugs. The number of examples of solving drug …

The syringic acid urea (SYRAUA) cocrystal was produced at room temperature using a slow
evaporation approach. The SYRAUA formed as orthorhombic crystal with the Cmca space …

Pharmaceutical cocrystals represent an emergent class of successful materials designed
based on crystal engineering principles, in which the limitations of the extant drugs are …

Abstract The promising amino 2-(2′-hydroxyphenyl) benzazole derivatives have taken
extensively attractions in biochemical and photochemical fields because of their strong …

Tuning mechanical performance of molecular materials is currently attractive owing to their
practical applications in pharmaceutical, food, and fine chemical industries and …

In this work, the cocrystallization approach was applied to itraconazole (ITR), a very slightly
soluble triazole antifungal drug, which led to the formation of two new solid forms of ITR with …

Sulfathiazole (ST) was investigated quantum chemically by DFT approach, surface analysis
by Hirshfeld and experimentally by NMR (FT-IR, UV-Visible 1H-NMR and 13C-NMR). The …

Multidrug solids have a potential use to efficiently treat and control a superfluity of medical
conditions. To address the current drawbacks of drug development in R&D, it was targeted …