Neural stem cells exist not only in the developing mammalian nervous system but also in the
adult nervous system of all mammalian organisms, including humans. Neural stem cells can …

The discovery of stem cells that can generate neural tissue has raised new possibilities for
repairing the nervous system. A rush of papers proclaiming adult stem cell plasticity has …

The remarkable developmental potential and replicative capacity of human embryonic stem
(ES) cells promise an almost unlimited supply of specific cell types for transplantation …

Demyelination contributes to loss of function after spinal cord injury, and thus a potential
therapeutic strategy involves replacing myelin-forming cells. Here, we show that …

▪ Abstract Mouse embryonic stem cells are continuous cell lines derived directly from the
fetal founder tissue of the preimplantation embryo. They can be expanded in culture while …

The long-term goal of nuclear transfer or alternative reprogramming approaches is to create
patient-specific donor cells for transplantation therapy, avoiding immunorejection, a major …

The discovery of mouse embryonic stem (ES) cells> 20 years ago represented a major
advance in biology and experimental medicine, as it enabled the routine manipulation of the …

Neural stem cells (NSCs) offer the potential to replace lost tissue after nervous system injury.
This study investigated whether grafts of NSCs (mouse clone C17. 2) could also specifically …

Stem cells are unique cell populations with the ability to undergo both self-renewal and
differentiation. A wide variety of adult mammalian tissues harbors stem cells, yet “adult” stem …

Entity or Function? specific adult stem cell may need to be expanded. Accordingly, adult
stem cells may not only act locally in the tissues in which they reside, but may also be …