Impact of hydrogen sulfide on mitochondrial and bacterial bioenergetics

VB Borisov, E Forte - International Journal of Molecular Sciences, 2021 - mdpi.com
This review focuses on the effects of hydrogen sulfide (H2S) on the unique bioenergetic
molecular machines in mitochondria and bacteria—the protein complexes of electron …

Redox properties of the membrane proteins from the respiratory chain

F Melin, P Hellwig - Chemical reviews, 2020 - ACS Publications
This review focuses on the electrochemical and spectroelectrochemical studies that gave
insight into redox potentials of the four mitochondrial complexes and their homologues from …

A large size-selective DNA nanopore with sensing applications

RP Thomsen, MG Malle, AH Okholm, S Krishnan… - Nature …, 2019 - nature.com
Transmembrane nanostructures like ion channels and transporters perform key biological
functions by controlling flow of molecules across lipid bilayers. Much work has gone into …

Biased cytochrome P450-mediated metabolism via small-molecule ligands binding P450 oxidoreductase

SB Jensen, S Thodberg, S Parween, ME Moses… - Nature …, 2021 - nature.com
Metabolic control is mediated by the dynamic assemblies and function of multiple redox
enzymes. A key element in these assemblies, the P450 oxidoreductase (POR), donates …

Single-particle combinatorial multiplexed liposome fusion mediated by DNA

MG Malle, PMG Löffler, SSR Bohr, MB Sletfjerding… - Nature Chemistry, 2022 - nature.com
Combinatorial high-throughput methodologies are central for both screening and discovery
in synthetic biochemistry and biomedical sciences. They are, however, often reliant on large …

Current problems and future avenues in proteoliposome research

AM Amati, S Graf, S Deutschmann… - Biochemical Society …, 2020 - portlandpress.com
Membrane proteins (MPs) are the gatekeepers between different biological compartments
separated by lipid bilayers. Being receptors, channels, transporters, or primary pumps, they …

Constructing artificial respiratory chain in polymer compartments: Insights into the interplay between bo3 oxidase and the membrane

N Marušič, L Otrin, Z Zhao, RB Lira… - Proceedings of the …, 2020 - National Acad Sciences
Cytochrome bo 3 ubiquinol oxidase is a transmembrane protein, which oxidizes ubiquinone
and reduces oxygen, while pumping protons. Apart from its combination with F1Fo-ATPase …

Direct observation of proton pumping by a eukaryotic P-type ATPase

S Veshaguri, SM Christensen, GC Kemmer, G Ghale… - Science, 2016 - science.org
In eukaryotes, P-type adenosine triphosphatases (ATPases) generate the plasma
membrane potential and drive secondary transport systems; however, despite their …

Rapid and highly stable membrane reconstitution by LAiR enables the study of physiological integral membrane protein functions

A Godoy-Hernandez, AH Asseri… - ACS Central …, 2023 - ACS Publications
Functional reintegration into lipid environments represents a major challenge for in vitro
investigation of integral membrane proteins (IMPs). Here, we report a new approach, termed …

Detergent-free functionalization of hybrid vesicles with membrane proteins using SMALPs

R Catania, J Machin, M Rappolt, SP Muench… - …, 2022 - ACS Publications
Hybrid vesicles (HVs) that consist of mixtures of block copolymers and lipids are robust
biomimetics of liposomes, providing a valuable building block in bionanotechnology …