Applications of biomaterials in 3D cell culture and contributions of 3D cell culture to drug development and basic biomedical research

Y Park, KM Huh, SW Kang - International Journal of Molecular Sciences, 2021 - mdpi.com
The process of evaluating the efficacy and toxicity of drugs is important in the production of
new drugs to treat diseases. Testing in humans is the most accurate method, but there are …

Recent advancement of decellularization extracellular matrix for tissue engineering and biomedical application

J Yang, H Dang, Y Xu - Artificial organs, 2022 - Wiley Online Library
Background Decellularized extracellular matrixs (dECMs) derived from organs and tissues
have emerged as a promising tool, as they encompass the characteristics of an ideal tissue …

Decellularization techniques for tissue engineering: towards replicating native extracellular matrix architecture in liver regeneration

I Allu, AK Sahi, M Koppadi, S Gundu… - Journal of Functional …, 2023 - mdpi.com
The process of tissue regeneration requires the utilization of a scaffold, which serves as a
structural framework facilitating cellular adhesion, proliferation, and migration within a …

Recent advances in liver engineering with decellularized scaffold

Q Dai, W Jiang, F Huang, F Song, J Zhang… - … in Bioengineering and …, 2022 - frontiersin.org
Liver transplantation is currently the only effective treatment for patients with end-stage liver
disease; however, donor liver scarcity is a notable concern. As a result, extensive endeavors …

[HTML][HTML] Decellularized extracellular matrix materials for treatment of ischemic cardiomyopathy

W Liu, X Zhang, X Jiang, B Dai, L Zhang, Y Zhu - Bioactive Materials, 2024 - Elsevier
Ischemic cardiomyopathy (ICM) affect millions of patients globally. Decellularized
extracellular matrix materials (dECM) have components, microstructure and mechanical …

Decellularized extracellular matrix: the role of this complex biomaterial in regeneration

AGP de Paula, JD de Lima, TSB Bastos… - ACS …, 2023 - ACS Publications
Organ transplantation is understood as a technique where an organ from a donor patient is
transferred to a recipient patient. This practice gained strength in the 20th century and …

Application of triple co-cultured cell spheroid model for exploring hepatotoxicity and metabolic pathway of AFB1

X Ma, J Sun, Y Ye, J Ji, X Sun - Science of the Total Environment, 2022 - Elsevier
The toxicity evaluation suffers from the absence of suitable models capable of replicating in
the co-cultured cell microenvironment and the function of specific tissues in vitro. Motivated …

In-vitro and in-vivo hemostat evaluation of decellularized liver extra cellular matrix loaded chitosan/gelatin spongy scaffolds for liver injury

TL Chu, G Tripathi, SH Bae, BT Lee - International Journal of Biological …, 2021 - Elsevier
Abstract Individually, Chitosan (C) and Gelatin (G) are increasingly being used for the
simulation and testing of surgical procedures. In the present study, at combination of …

The journey of decellularized vessel: from laboratory to operating room

C Kang, H Yang - Frontiers in Bioengineering and Biotechnology, 2024 - frontiersin.org
Over the past few decades, there has been a remarkable advancement in the field of
transplantation. But the shortage of donors is still an urgent problem that requires immediate …

Self-Calibrating Lanthanide Infinite Coordination Polymer Constructs Fluorescent Probes: A Sensitive Approach for Early Diagnosis of Hepatocellular Carcinoma and …

T Wang, J Hu, J Xu, Y Ji, R Li - ACS Applied Materials & Interfaces, 2023 - ACS Publications
The development of a self-calibrating ratio fluorescence probe without the need for
additional substrates is a major advancement in biosensing. In this study, at room …