[HTML][HTML] Functional mechanisms of TRPS1 in disease progression and its potential role in personalized medicine

L Yang, X Gong, J Wang, Q Fan, J Yuan, X Yang… - … -Research and Practice, 2022 - Elsevier
The gene of transcriptional repressor GATA binding 1 (TRPS1), as an atypical GATA
transcription factor, has received considerable attention in a plethora of physiological and …

A new perspective on the function of Tissue Non-Specific Alkaline Phosphatase: from bone mineralization to intra-cellular lipid accumulation

CL Bartlett, EM Cave, NJ Crowther… - Molecular and Cellular …, 2022 - Springer
Tissue-nonspecific alkaline phosphatase (TNAP) is one of four isozymes, which include
germ cell, placental and intestinal alkaline phosphatases. The TNAP isozyme has 3 isoforms …

MicroRNA-196a-5p overexpression in Wharton's jelly umbilical cord stem cells promotes their osteogenic differentiation and new bone formation in bone defects in the …

Y Wang, S Zhang, H Yang, Y Cao, D Yu, Y Zhao… - Cell and Tissue …, 2022 - Springer
The peri-tooth root alveolar loss often does not have sufficient space for repair material
transplantation and plasticity. Mesenchymal stem cell (MSC) sheets have an advantage in …

Knockdown of SERPINB2 enhances the osteogenic differentiation of human bone marrow mesenchymal stem cells via activation of the Wnt/β-catenin signalling …

K Hang, L Ying, J Bai, Y Wang, Z Kuang, D Xue… - Stem Cell Research & …, 2021 - Springer
Background Globally, bone fractures are the most common musculoskeletal trauma, and
approximately 8–10% of cases that fall into the categories of delayed or non-union healing …

SERPINB2, an Early Responsive Gene to Epigallocatechin Gallate, Inhibits Migration and Promotes Apoptosis in Esophageal Cancer Cells

Z Chen, Y Wei, Y Zheng, H Zhu, Q Teng, X Lin, F Wu… - Cells, 2022 - mdpi.com
Esophageal cancer is a lethal disease that frequently occurs in developing countries, the
incidence of which could be declined by drinking EGCG-enriched drinks or food. SERPINB2 …

Deficiency of mineralization-regulating transcription factor trps1 compromises quality of dental tissues and increases susceptibility to dental caries

M Socorro, P Hoskere, C Roberts… - Frontiers in dental …, 2022 - frontiersin.org
Dental caries is the most common chronic disease in children and adults worldwide. The
complex etiology of dental caries includes environmental factors as well as host genetics …

Analysis of the function, mechanism and clinical application prospect of TRPS1, a new marker for breast cancer

X He, H Huang, Y Liu, H Li, H Ren - Gene, 2024 - Elsevier
It has been discovered that Trichorhinophalangeal Syndrome-1 (TRPS1), a novel member of
the GATA transcription factor family, participates in both normal physiological processes and …

Calcium and phosphate and their role in matrix vesicles: A biological view

L Hayann, P Ciancaglini, AP Ramos, D Napierala - Mineralizing Vesicles, 2024 - Elsevier
Abstract Calcium (Ca 2+) and phosphate ions (PO 4 3−/P i) are indispensable for all
fundamental biological processes. The bones are the major reservoir of these ions in the …

The influence of MDR1 expression regulated by miR-138 through TRPS1 signaling pathway on multidrug resistance of osteosarcoma and formation of bacterial …

X Fang, L Zhu, Q Wu, X Zhong… - Cellular and Molecular …, 2023 - mail.cellmolbiol.org
This study was to investigate the effect of microribonucleic acid (mi-RNA) on the resistance
of human multidrug resistance gene 1 (MDR1) to osteosarcoma through the Trico-nasal …

Characterization of the consequences of Trps1 deficiency in osteoblasts on bone formation

P Keskinidis - 2023 - search.proquest.com
TRPS1 is a gene that encodes a zinc-finger transcription factor named TRPS1. Mutations in
the TRPS1 gene cause a rare genetic disease called trichorhinophalangeal syndrome …