Colorectal cancer in inflammatory bowel disease: review of the evidence

DS Keller, A Windsor, R Cohen, M Chand - Techniques in coloproctology, 2019 - Springer
Inflammatory bowel disease (IBD)-related colorectal cancer (CRC) is responsible for
approximately 2% of the annual mortality from CRC overall, but 10–15% of the annual …

[HTML][HTML] Inflammatory bowel disease and colorectal cancer: epidemiology, etiology, surveillance, and management

Y Sato, S Tsujinaka, T Miura, Y Kitamura, H Suzuki… - Cancers, 2023 - mdpi.com
Simple Summary Although the incidence of inflammatory bowel disease (IBD)-related
cancer has been decreasing, its prognosis remains worse than that of non-IBD-related …

Moringa oleifera leaves alleviated inflammation through downregulation of IL-2, IL-6, and TNF-α in a colitis-associated colorectal cancer model

ML Cuellar-Núñez, EG De Mejia… - Food Research …, 2021 - Elsevier
New chemopreventive alternatives are needed due to the rising worldwide incidence of
colorectal cancer. The objective was to evaluate the chemopreventive activity of Moringa …

Survival outcomes and clinicopathological features in inflammatory bowel disease-associated colorectal cancer: a systematic review and meta-analysis

C Lu, J Schardey, T Zhang, A Crispin, U Wirth… - Annals of …, 2022 - journals.lww.com
Objective: The aim of our study was to conduct a systematic review and meta-analysis
comparing the survival outcomes of IBD-associated and non-IBD-associated CRC …

Precancer in ulcerative colitis: the role of the field effect and its clinical implications

KT Baker, JJ Salk, TA Brentnall, RA Risques - Carcinogenesis, 2018 - academic.oup.com
Cumulative evidence indicates that a significant proportion of cancer evolution may occur
before the development of histological abnormalities. While recent improvements in DNA …

HNE and cholesterol oxidation products in colorectal inflammation and carcinogenesis

D Rossin, S Calfapietra, B Sottero, G Poli… - Free Radical Biology and …, 2017 - Elsevier
Consistent experimental data suggest the importance of inflammation-associated oxidative
stress in colorectal cancer (CRC) pathogenesis. Inflammatory bowel disease with chronic …

Biosensors for spatiotemporal detection of reactive oxygen species in cells and tissues

M Erard, S Dupré-Crochet… - American Journal of …, 2018 - journals.physiology.org
Redox biology has become a major issue in numerous areas of physiology. Reactive
oxygen species (ROS) have a broad range of roles from signal transduction to growth …

[HTML][HTML] Quantitative or qualitative transcriptional diagnostic signatures? A case study for colorectal cancer

Q Guan, H Yan, Y Chen, B Zheng, H Cai, J He, K Song… - BMC genomics, 2018 - Springer
Background Due to experimental batch effects, the application of a quantitative
transcriptional signature for disease diagnoses commonly requires inter-sample data …

[HTML][HTML] The ω-3 polyunsaturated fatty acids prevented colitis-associated carcinogenesis through blocking dissociation of β-catenin complex, inhibiting COX-2 through …

YM Han, M Jeong, JM Park, MY Kim, EJ Go, JY Cha… - Oncotarget, 2016 - ncbi.nlm.nih.gov
Numerous studies have demonstrated that diets containing an increased ratio of ω-6: ω-3
polyunsaturated fatty acids (PUFAs) are a risk factor for colon cancer and might affect …

Nuclear receptors in the pathogenesis and management of inflammatory bowel disease

L Ning, X Lou, F Zhang, G Xu - Mediators of inflammation, 2019 - Wiley Online Library
Nuclear receptors (NRs) are ligand‐dependent transcription factors that regulate the
transcription of target genes. Previous epidemiological and genetic studies have …