Chemical synthesis of glycosaminoglycans
M Mende, C Bednarek, M Wawryszyn, P Sauter… - Chemical …, 2016 - ACS Publications
Glycosaminoglycans (GAGs) as one major part of the glycocalyx are involved in many
essential biological cell processes, as well as in many courses of diseases. Because of the …
essential biological cell processes, as well as in many courses of diseases. Because of the …
What is the sugar code?
HJ Gabius, M Cudic, T Diercks, H Kaltner… - …, 2022 - Wiley Online Library
A code is defined by the nature of the symbols, which are used to generate information‐
storing combinations (eg oligo‐and polymers). Like nucleic acids and proteins, oligo‐and …
storing combinations (eg oligo‐and polymers). Like nucleic acids and proteins, oligo‐and …
Exploring functional pairing between surface glycoconjugates and human galectins using programmable glycodendrimersomes
Precise translation of glycan-encoded information into cellular activity depends critically on
highly specific functional pairing between glycans and their human lectin counter receptors …
highly specific functional pairing between glycans and their human lectin counter receptors …
Analysis of carbohydrates and glycoconjugates by matrix‐assisted laser desorption/ionization mass spectrometry: An update for 2013–2014
DJ Harvey - Mass Spectrometry Reviews, 2018 - Wiley Online Library
This review is the eighth update of the original article published in 1999 on the application of
Matrix‐assisted laser desorption/ionization mass spectrometry (MALDI) mass spectrometry …
Matrix‐assisted laser desorption/ionization mass spectrometry (MALDI) mass spectrometry …
Automated glycan assembly of oligo-N-acetyllactosamine and keratan sulfate probes to study virus-glycan interactions
HS Hahm, F Broecker, F Kawasaki, M Mietzsch… - Chem, 2017 - cell.com
Summary Oligo-N-acetyllactosamine (LacNAc) and keratan sulfate (KS) glycans exert
crucial functions in disease-relevant processes, including cancer formation, inflammation …
crucial functions in disease-relevant processes, including cancer formation, inflammation …
Orthogonal protecting group strategies in carbohydrate chemistry
K Agoston, H Streicher, P Fuegedi - Tetrahedron: Asymmetry, 2016 - Elsevier
A large number of different sets of orthogonal protecting groups have been developed and
used in carbohydrate chemistry over the last decade. These orthogonal sets are collected …
used in carbohydrate chemistry over the last decade. These orthogonal sets are collected …
Synthesis of type-I and type-II lacNAc-repeating oligosaccharides as the backbones of tumor-associated lewis antigens
R Phang, CH Lin - Frontiers in Immunology, 2022 - frontiersin.org
Type-I and Type-II LacNAc are Gal-GlcNAc disaccharides bearing a β1, 3-or β1, 4-linkage
respectively. They exist as the backbones of Lewis antigens that are highly expressed in …
respectively. They exist as the backbones of Lewis antigens that are highly expressed in …
Probing sulfatide-tissue lectin recognition with functionalized glycodendrimersomes
The small 3-O-sulfated galactose head group of sulfatides, an abundant glycosphingolipid
class, poses the (sphinx-like) riddle on involvement of glycan bridging by tissue lectins …
class, poses the (sphinx-like) riddle on involvement of glycan bridging by tissue lectins …
Teaming up synthetic chemistry and histochemistry for activity screening in galectin-directed inhibitor design
R Roy, Y Cao, H Kaltner, N Kottari, TC Shiao… - Histochemistry and cell …, 2017 - Springer
A hallmark of endogenous lectins is their ability to select a few distinct glycoconjugates as
counterreceptors for functional pairing from the natural abundance of cellular glycoproteins …
counterreceptors for functional pairing from the natural abundance of cellular glycoproteins …
Structural insight into the binding of human galectins to corneal keratan sulfate, its desulfated form and related saccharides
Glycosaminoglycan chains of keratan sulfate proteoglycans appear to be physiologically
significant by pairing with tissue lectins. Here, we used NMR spectroscopy and molecular …
significant by pairing with tissue lectins. Here, we used NMR spectroscopy and molecular …