Pulmonary hypertension is defined as a resting mean pulmonary artery pressure of 25 mm
Hg or above. This review deals with pulmonary arterial hypertension (PAH), a type of …

Background Pulmonary arterial hypertension is characterized by pulmonary vascular
remodeling, cellular proliferation, and poor long-term outcomes. Dysfunctional bone …

This review summarizes an expanding body of knowledge indicating that failure to resolve
inflammation and altered immune processes underlie the development of pulmonary arterial …

Regulated cell death is a major mechanism to eliminate damaged, infected, or superfluous
cells. Previously, apoptosis was thought to be the only regulated cell death mechanism; …

Genetic evidence implicates the loss of bone morphogenetic protein type II receptor (BMPR-
II) signaling in the endothelium as an initiating factor in pulmonary arterial hypertension …

Pulmonary arterial hypertension is a progressive disorder in which endothelial dysfunction
and vascular remodeling obstruct small pulmonary arteries, resulting in increased …

Background Pulmonary arterial hypertension is a devastating disease with high mortality.
Familial cases of pulmonary arterial hypertension are usually characterized by autosomal …

Rationale: The impact of modern treatments of pulmonary arterial hypertension (PAH) on
pulmonary vascular pathology remains unknown. Objectives: To assess the spectrum of …

Pulmonary arterial hypertension (PAH) is a disease characterized by progressive
remodeling of the distal pulmonary arteries, resulting in the loss of vascular cross-sectional …

Dysfunctional bone morphogenetic protein receptor-2 (BMPR2) signaling is implicated in the
pathogenesis of pulmonary arterial hypertension (PAH). We used a transcriptional high …