Introduction: Cancer is a devastating disease; however, several therapeutic advances have
recently been made, wherein EGFR and its family members have emerged as useful …

Mucins (MUC) protect epithelial barriers from environmental insult to maintain homeostasis.
However, their aberrant overexpression and glycosylation in various malignancies facilitate …

Epithelia are protected from adverse conditions by a mucous barrier. The secreted and
transmembrane mucins that constitute the mucous barrier are largely unrecognized as …

Breast cancer is the most frequently diagnosed cancer and the principal cause of mortality
by malignancy in women and represents a main problem for public health worldwide. Tumor …

Pancreatic ductal adenocarcinoma (PDA) is one of the deadliest cancers and is projected to
soon be the second leading cause of cancer death. Median survival of PDA patients is 6–10 …

Pancreatic cancer remains a lethal malignancy with poor prognosis owing to therapeutic
resistance, frequent recurrence and the absence of treatment strategies that specifically …

Mucins (MUC) are high molecular weight O-linked glycoproteins whose primary functions
are to hydrate, protect, and lubricate the epithelial luminal surfaces of the ducts within the …

Low-grade fibromyxoid sarcoma (LGFMS) is a distinctive fibroblastic neoplasm that is
characterized by alternating collagenous and myxoid areas, deceptively bland spindle cell …

Sclerosing epithelioid fibrosarcoma (SEF) is a rare aggressive fibroblastic neoplasm
composed of cords of epithelioid cells embedded in a dense collagenous stroma. The …

Mucins are high molecular weight, multifunctional glycoproteins comprised of two structural
classes—the large transmembrane mucins and the gel-forming or secreted mucins. The …