The antitumor efficiency and clinical translation of traditional nanomedicines is mainly
restricted by low drug loading, complex preparation technology, and potential toxicity …

The peripheral nervous system can be vulnerable to the toxic action of several drugs since it
is not protected as effectively as the central nervous system from noxious exogenous agents …

Acclaimed by the worldwide medical community as" a staple reference text in the medical
oncologist's library"(JAMA), DeVita, Hellman, and Rosenberg's Cancer: Principles and …

Microbes have made a phenomenal contribution to the health and well-being of people
throughout the world. In addition to producing many primary metabolites, such as amino …

Over geological time, photosynthetic carbon fixation in the oceans has exceeded respiratory
oxidation of organic carbon. The imbalance between the two processes has resulted in the …

Microtubules have long been considered an ideal target for anticancer drugs because of the
essential role they play in mitosis, forming the dynamic spindle apparatus. As such, there is …

Microtubules, major structural components in cells, are the target of a large and diverse
group of natural product anticancer drugs. Given the success of this class of drugs in cancer …

Natural products are the most consistently successful source of drug leads. Despite this,
their use in drug discovery has fallen out of favour. Natural products continue to provide …

The extrusion of anticancer drugs by members of the ATP-binding cassette (ABC)
transporter family is one of the most widely recognized mechanisms of multidrug resistance …

Plants, marine organisms, and microorganisms have evolved complex chemical defense
and signaling systems that are designed to protect them from predators and provide other …