[HTML][HTML] Targeted therapeutics and novel signaling pathways in non-alcohol-associated fatty liver/steatohepatitis (NAFL/NASH)
X Xu, KL Poulsen, L Wu, S Liu, T Miyata… - Signal transduction and …, 2022 - nature.com
Non-alcohol-associated fatty liver/steatohepatitis (NAFL/NASH) has become the leading
cause of liver disease worldwide. NASH, an advanced form of NAFL, can be progressive …
cause of liver disease worldwide. NASH, an advanced form of NAFL, can be progressive …
Age-related mitochondrial dysfunction as a key factor in COVID-19 disease
DJM Fernández-Ayala, P Navas… - Experimental gerontology, 2020 - Elsevier
SARS-CoV-2 causes a severe pneumonia (COVID-19) that affects essentially elderly
people. In COVID-19, macrophage infiltration into the lung causes a rapid and intense …
people. In COVID-19, macrophage infiltration into the lung causes a rapid and intense …
[HTML][HTML] Role of Coenzyme Q10 in Health and Disease: An Update on the Last 10 Years (2010–2020)
I Cirilli, E Damiani, PV Dludla, I Hargreaves… - Antioxidants, 2021 - mdpi.com
The present review focuses on preclinical and clinical studies conducted in the last decade
that contribute to increasing knowledge on Coenzyme Q10's role in health and disease …
that contribute to increasing knowledge on Coenzyme Q10's role in health and disease …
[HTML][HTML] Detrimental effects of lipid peroxidation in type 2 diabetes: Exploring the neutralizing influence of antioxidants
SC Shabalala, R Johnson, AK Basson, K Ziqubu… - Antioxidants, 2022 - mdpi.com
Lipid peroxidation, including its prominent byproducts such as malondialdehyde (MDA) and
4-hydroxy-2-nonenal (4-HNE), has long been linked with worsened metabolic health in …
4-hydroxy-2-nonenal (4-HNE), has long been linked with worsened metabolic health in …
Adipokines as a therapeutic target by metformin to improve metabolic function: A systematic review of randomized controlled trials
Metformin is a widely used glucose-lowering drug, although its impact on adipose tissue
function remains elusive. Adipose tissue-derived molecules regulate diverse physiological …
function remains elusive. Adipose tissue-derived molecules regulate diverse physiological …
Effect of coenzyme Q10 on cardiac function and survival in heart failure: an overview of systematic reviews and meta-analyses
E Alarcón-Vieco, I Martínez-García… - Food & Function, 2023 - pubs.rsc.org
Heart failure (HF) is associated with a deficiency in blood levels of coenzyme Q10 (CoQ10),
and its supplementation has been proposed. The aim of this systematic review was to …
and its supplementation has been proposed. The aim of this systematic review was to …
Mitochondrial dysfunction in mouse livers depleted of iron chaperone PCBP1
Iron is an essential nutrient that forms cofactors required for the activity of hundreds of
cellular proteins. However, iron can be toxic and must be precisely managed. Poly r (C) …
cellular proteins. However, iron can be toxic and must be precisely managed. Poly r (C) …
[HTML][HTML] Effects of Coenzyme Q10 supplementation on biomarkers of oxidative stress in adults: a GRADE-Assessed systematic review and updated Meta-analysis of …
S Dai, Z Tian, D Zhao, Y Liang, M Liu, Z Liu, S Hou… - Antioxidants, 2022 - mdpi.com
Evidence shows that exogenous CoQ10 supplementation may potentially attenuate
oxidative stress status. However, its effective dose and evidence certainty require further …
oxidative stress status. However, its effective dose and evidence certainty require further …
[HTML][HTML] Alleviating effects of coenzyme Q10 supplements on biomarkers of inflammation and oxidative stress: results from an umbrella meta-analysis
S Dabbaghi Varnousfaderani, V Musazadeh… - Frontiers in …, 2023 - frontiersin.org
Introduction: Although several meta-analyses support the positive effect of coenzyme Q10
(CoQ10) on biomarkers of oxidative stress and inflammation, the results of some other …
(CoQ10) on biomarkers of oxidative stress and inflammation, the results of some other …
Coenzyme Q10 in atherosclerosis
M Liao, X He, Y Zhou, W Peng, XM Zhao… - European Journal of …, 2024 - Elsevier
Atherosclerotic disease is a chronic disease that predominantly affects the elderly and is the
most common cause of cardiovascular death worldwide. Atherosclerosis is closely related to …
most common cause of cardiovascular death worldwide. Atherosclerosis is closely related to …