Single-cell approaches are quickly changing our view on biological systems by increasing
the spatiotemporal resolution of our analyses to the level of the individual cell. The field of …

The rapid and enthusiastic adoption of single-cell RNA sequencing (scRNA-seq) has
demonstrated that this technology is far more than just another way to perform transcriptome …

In plant tissue culture, callus forms from detached explants in response to a high-auxin-to-
low-cytokinin ratio on callus-inducing medium. Callus is a group of pluripotent cells because …

INTRODUCTION The brain is responsible for cognition, behavior, and much of what makes
us uniquely human. The development of the brain is a highly complex process, and this …

To understand and engineer plant metabolism, we need a comprehensive and accurate
annotation of all metabolic information across plant species. As a step towards this goal, we …

Immune cells infiltrating tumors can have important impact on tumor progression and
response to therapy. We present an efficient algorithm to simultaneously estimate the …

High-throughput single-cell RNA sequencing (scRNA-seq) is becoming a cornerstone of
developmental research, providing unprecedented power in understanding dynamic …

Different plant species within the grasses were parallel targets of domestication, giving rise
to crops with distinct evolutionary histories and traits. Key traits that distinguish these species …

Single-cell RNA sequencing (scRNA-seq) has been used extensively to study cell-specific
gene expression in animals, but it has not been widely applied to plants. Here, we describe …

Single-cell transcriptome profiling of heterogeneous tissues can provide high-resolution
windows into developmental dynamics and environmental responses, but its application to …