The hallmark and crosstalk of immune cells after intracerebral hemorrhage: Immunotherapy perspectives

W Zhang, Q Wu, S Hao, S Chen - Frontiers in Neuroscience, 2023 - frontiersin.org
Intracerebral hemorrhage (ICH) is one of the most dangerous types of strokes with a high
morbidity and mortality rate. Currently, the treatment of ICH is not well developed, mainly …

Caring for patients with diabetes in stroke neurology

WN Kernan, R Forman, SE Inzucchi - Stroke, 2023 - Am Heart Assoc
Diabetes is a heterogeneous disease that affects 9% of the world's population (11% in the
United States). The consequences of diabetes for the brain are severe; it nearly doubles a …

Canagliflozin, an Inhibitor of the Na+-Coupled D-Glucose Cotransporter, SGLT2, Inhibits Astrocyte Swelling and Brain Swelling in Cerebral Ischemia

B Shim, JA Stokum, M Moyer, N Tsymbalyuk… - Cells, 2023 - mdpi.com
Brain swelling is a major cause of death and disability in ischemic stroke. Drugs of the
gliflozin class, which target the Na+-coupled D-glucose cotransporter, SGLT2, are approved …

The stress hyperglycemia ratio is associated with the development of cerebral edema and poor functional outcome in patients with acute cerebral infarction

Y Deng, S Wu, J Liu, M Liu, L Wang, JC Wan… - Frontiers in Aging …, 2022 - frontiersin.org
Background and purpose Absolute hyperglycemia at admission has been shown to be
associated with the development of cerebral edema (CED) after acute cerebral infarction …

Clinical significance and influencing factors of microvascular tissue reperfusion after macrovascular recanalization

X Bai, F Yu, Q Tian, W Li, A Sha, W Cao, Y Feng… - Translational Stroke …, 2023 - Springer
The relevance of impaired microvascular tissue reperfusion despite successful
macrovascular angiographic reperfusion (no-reflow) in acute ischemic stroke (AIS) remains …

Predictors and outcome of malignant cerebral edema after successful reperfusion in anterior circulation stroke

M Pu, J Chen, Z Chen, Z Li, Z Li, Y Tang, Q Li - Journal of Stroke and …, 2023 - Elsevier
Background and objective Risk factors and predictors of malignant cerebral edema (MCE)
after successful endovascular thrombectomy (EVT) were not fully explored. This study aimed …

Anaerobic Glycolysis and Ischemic Stroke: From Mechanisms and Signaling Pathways to Natural Product Therapy

J Pu, J Han, J Yang, L Yu, H Wan - ACS Chemical Neuroscience, 2024 - ACS Publications
Ischemic stroke is a serious condition that results in high rates of illness and death.
Anaerobic glycolysis becomes the primary means of providing energy to the brain during …

Higher serum E-selectin levels associated with malignant brain edema after endovascular thrombectomy for ischemic stroke: a pilot study

F Zhou, M Du, YE, S Chen, W Wang, H Shi, J Zhou… - Brain Sciences, 2023 - mdpi.com
Abstract Background and Purpose: Little is known about the effect of soluble adhesion
molecules on malignant brain edema (MBE) after endovascular thrombectomy (EVT). This …

Large vessel occlusion stroke outcomes in diabetic vs. non-diabetic patients with acute stress hyperglycemia

H Duan, HJ Yun, GB Rajah, F Che, Y Wang… - Frontiers in …, 2023 - frontiersin.org
Objective This study assesses whether stress-induced hyperglycemia is a predictor of poor
outcome at 3 months for patients with acute ischemic stroke (AIS) treated by endovascular …

Early venous filling after mechanical thrombectomy in acute ischemic stroke due to large vessel occlusion in anterior circulation

Y Li, W Cao, X Xu, T Li, Y Chen, Y Wang… - Journal of …, 2024 - jnis.bmj.com
Background The significance of early venous filling (EVF) after mechanical thrombectomy
(MT) in acute ischemic stroke (AIS) is not fully understood. In this study, we aimed to …