Obesity and colorectal cancer

M Bardou, AN Barkun, M Martel - Gut, 2013 - gut.bmj.com
Excess body weight, as defined by the body mass index (BMI), has been associated with
several diseases and includes subjects who are overweight (BMI≥ 25–29.9 kg/m2) or …

Roles of adipokines in digestive diseases: markers of inflammation, metabolic alteration and disease progression

ML Chang, Z Yang, SS Yang - International journal of molecular sciences, 2020 - mdpi.com
Adipose tissue is a highly dynamic endocrine tissue and constitutes a central node in the
interorgan crosstalk network through adipokines, which cause pleiotropic effects, including …

Mechanisms of obesity-induced gastrointestinal neoplasia

JO Alemán, LH Eusebi, L Ricciardiello, K Patidar… - Gastroenterology, 2014 - Elsevier
Obesity is among the fastest growing diseases worldwide; treatment is inadequate, and
associated disorders, including gastrointestinal cancers, have high morbidity and mortality …

Oncogenic role and therapeutic target of leptin signaling in breast cancer and cancer stem cells

S Guo, M Liu, G Wang, M Torroella-Kouri… - … et Biophysica Acta (BBA …, 2012 - Elsevier
Significant correlations between obesity and incidence of various cancers have been
reported. Obesity, considered a mild inflammatory process, is characterized by a high level …

[PDF][PDF] Associations between adipokines and obesity-related cancer

G Paz-Filho, EL Lim, ML Wong, J Licinio - Front Biosci, 2011 - researchgate.net
[Frontiers in Bioscience 16, 1634-1650, January 1, 2011] 1634 Associations between
adipokines and obesity-related cancer Gilbert Page 1 [Frontiers in Bioscience 16, 1634-1650 …

[HTML][HTML] Obesity-induced thymic involution and cancer risk

MK Lagou, GS Karagiannis - Seminars in Cancer Biology, 2023 - Elsevier
Declining thymic functions associated either with old age (ie, age-related thymic involution),
or with acute involution as a result of stress, infectious disease, or cytoreductive therapies …

Thymoquinone suppresses growth and induces apoptosis via generation of reactive oxygen species in primary effusion lymphoma

AR Hussain, M Ahmed, S Ahmed, P Manogaran… - Free radical biology and …, 2011 - Elsevier
We provide evidence that thymoquinone (TQ), a natural compound isolated from Nigella
sativa, induces growth inhibition and apoptosis in several primary effusion lymphoma (PEL) …

Cancer chemopreventive effects of lycopene: suppression of MMP-7 expression and cell invasion in human colon cancer cells

MC Lin, FY Wang, YH Kuo, FY Tang - Journal of agricultural and …, 2011 - ACS Publications
Clinical studies indicate that high blood levels of leptin or matrix metalloproteinase-7 (MMP-
7; matrilysin) proteins are associated with tumor progression of human colorectal cancer …

Leptin and gastro‐intestinal malignancies

JM Howard, GP Pidgeon, JV Reynolds - Obesity Reviews, 2010 - Wiley Online Library
Obesity is a well‐established risk factor for the development and mortality from several
cancers, including adenocarcinoma of the oesophagus, oesophago‐gastric junction and …

Molecular mechanisms linking adipokines to obesity-related colon cancer: focus on leptin

JE Drew - Proceedings of the Nutrition Society, 2012 - cambridge.org
Obesity is linked to increased risk of colon cancer, currently the third most common cancer.
Consequently rising levels of obesity worldwide are likely to significantly impact on obesity …