Home as the new frontier for the treatment of COVID-19: the case for anti-inflammatory agents

N Perico, M Cortinovis, F Suter… - The Lancet Infectious …, 2023 - thelancet.com
Summary COVID-19, caused by SARS-CoV-2, is characterised by a broad spectrum of
symptom severity that requires varying amounts of care according to the different stages of …

Coagulopathy and fibrinolytic pathophysiology in COVID-19 and SARS-CoV-2 vaccination

S Yamada, H Asakura - International Journal of Molecular Sciences, 2022 - mdpi.com
Coronavirus Disease 2019 (COVID-19) is caused by severe acute respiratory syndrome
coronavirus 2 (SARS-CoV-2) and is frequently complicated by thrombosis. In some cases of …

Baricitinib in patients admitted to hospital with COVID-19 (RECOVERY): a randomised, controlled, open-label, platform trial and updated meta-analysis

O Abani, A Abbas, F Abbas, J Abbas, K Abbas… - The Lancet, 2022 - thelancet.com
Background We aimed to evaluate the use of baricitinib, a Janus kinase (JAK) 1–2 inhibitor,
for the treatment of patients admitted to hospital with COVID-19. Methods This randomised …

Thromboembolic prevention and anticoagulant therapy during the COVID-19 pandemic: updated clinical guidance from the anticoagulation forum

GD Barnes, A Burnett, A Allen, J Ansell… - Journal of thrombosis …, 2022 - Springer
Thromboembolism is a common and deadly consequence of COVID-19 infection for
hospitalized patients. Based on clinical evidence pre-dating the COVID-19 pandemic and …

Microvascular thrombosis as a critical factor in severe COVID-19

PP Wadowski, B Panzer, A Józkowicz… - International Journal of …, 2023 - mdpi.com
Platelet–endothelial interactions have a critical role in microcirculatory function, which
maintains tissue homeostasis. The subtle equilibrium between platelets and the vessel wall …

Immunomodulatory therapy in children with paediatric inflammatory multisystem syndrome temporally associated with SARS-CoV-2 (PIMS-TS, MIS-C; RECOVERY): a …

SN Faust, R Haynes, CE Jones, N Staplin… - The Lancet Child & …, 2024 - thelancet.com
Background Paediatric multisystem inflammatory syndrome temporally associated with
SARS-CoV-2 (PIMS-TS), also known as multisystem inflammatory syndrome in children (MIS …

Long-term hypercoagulability, endotheliopathy and inflammation following acute SARS-CoV-2 infection

A Boccatonda, E Campello, C Simion… - Expert Review of …, 2023 - Taylor & Francis
Introduction both symptomatic and asymptomatic SARS-CoV-2 infections–coined
Coronavirus disease 2019 (COVID-19)–have been linked to a higher risk of cardiovascular …

Acute coronary syndrome in the COVID-19 era—differences and dilemmas compared to the pre-COVID-19 era

R Lasica, L Djukanovic, I Mrdovic, L Savic… - Journal of Clinical …, 2022 - mdpi.com
The COVID-19 pandemic has led to numerous negative implications for all aspects of
society. Although COVID-19 is a predominant lung disease, in 10–30% of cases, it is …

Aspirin in COVID-19: Pros and cons

R Zareef, M Diab, T Al Saleh, A Makarem… - Frontiers in …, 2022 - frontiersin.org
Since its emergence, the COVID-19 pandemic has been ravaging the medical and
economic sectors even with the significant vaccination advances. In severe presentations …

Antiplatelet therapy for patients with COVID-19: Systematic review and meta-analysis of observational studies and randomized controlled trials

X Zong, X Wang, Y Liu, Z Li, W Wang, D Wei… - Frontiers in …, 2022 - frontiersin.org
Background Hyperinflammation and coagulopathy are hallmarks of COVID-19 and
synergistically contribute to illness progression. Antiplatelet agents have been proposed as …