One pivotal aspect of early pregnancy is decidualization. The decidualization process
includes two components: the differentiation of endometrial stromal cells to decidual stromal …

During pregnancy, cell senescence at the maternal–fetal interface is required for maternal
well-being, placental development, and fetal growth. However, recent reports have shown …

In preparation for a potential pregnancy, the endometrium of the uterus changes into a
temporary structure called the decidua. Senescent decidual stromal cells (DSCs) are …

According to the current data, the endometrium acts as a “sensor” of embryo quality, which
promotes the implantation of euploid embryos and prevents the implantation and/or …

Decidualization denotes the process of inflammatory reprogramming of endometrial stromal
cells (EnSC) into specialized decidual cells (DC). During this process, EnSC are subjected …

Polycystic ovary syndrome (PCOS) is a common endocrine disorder affecting fertility and
mental health among women of reproductive age. In addition to anovulation and …

Decidualization of human endometrial stromal cells (hESCs) is essential for the
maintenance of pregnancy, which depends on the fine-tuned regulation of hESCs survival …

In each menstrual cycle, progesterone acting on estrogen-primed endometrium elicits an
inflammatory decidual reaction, rendering it poised for embryo implantation and …