Insulin resistance (IR) plays a crucial role in the development and progression of
metabolism-related diseases such as diabetes, hypertension, tumors, and nonalcoholic fatty …

Cardiovascular disease (CVD) remains a highly prevalent cause of morbidity and mortality,
both in the United States and worldwide. In parallel with the development of new and …

Obstructive sleep apnoea is an increasingly common disorder of repeated upper airway
collapse during sleep, leading to oxygen desaturation and disrupted sleep. Features include …

Excess intra-abdominal adipose tissue accumulation, often termed visceral obesity, is part of
a phenotype including dysfunctional subcutaneous adipose tissue expansion and ectopic …

There is currently limited understanding of the genetic aetiology of obstructive sleep apnoea
(OSA). We aimed to identify genetic loci associated with OSA risk, and to test if OSA and its …

Background Obesity and obstructive sleep apnea tend to coexist and are associated with
inflammation, insulin resistance, dyslipidemia, and high blood pressure, but their causal …

Recent studies have demonstrated that obstructive sleep apnea (OSA) is associated with the
development and evolution of nonalcoholic fatty liver disease (NAFLD), independent of …

Obstructive sleep apnea (OSA) adversely affects multiple organs and systems, with
particular relevance to cardiovascular disease. Several conditions associated with OSA …

Experimental approaches directed at addressing these issues are limited by several
considerations. First, the close association between obesity and OSA often obscures …

Adult obstructive sleep apnoea (OSA) is associated with cognitive dysfunction. While many
review articles have attempted to summarize the evidence for this association, it remains …