Amyotrophic lateral sclerosis (ALS) is a poorly treated multifactorial neurodegenerative
disease associated with multiple cell types and subcellular organelles. As with other …

Background Epilepsy is a prevalent disorder of the central nervous system. Approximately,
one-third of patients show resistance to pharmacological interventions. The pathogenesis of …

All current drug treatments for epilepsy, a neurological disorder affecting over 50 million
people (,) merely treat symptoms, and a third of patients do not respond to medication. There …

Epilepsy is a prevalent chronic neurological disorder characterized by recurrent seizures
and brain dysfunction. Existing antiepileptic drugs (AEDs) mainly act on neurons and …

Epilepsy is an abnormal neurologic disorder distinguished by the recurrent manifestation of
seizures, and the precise underlying mechanisms for its development and progression …

Selective Neuronal Knockout of STAT3 Function Inhibits Epilepsy Progression, Improves
Cognition, and Restores Dysregulated Gene Networks in a Temporal Lobe Epilepsy Model …

Tuberous sclerosis complex (TSC) is a rare genetic disease that results in the system-wide
growth of benign lesions. TSC patients often present with brain tumours and TSC-associated …