Nanoparticle radio-enhancement: principles, progress and application to cancer treatment
Z Kuncic, S Lacombe - Physics in Medicine & Biology, 2018 - iopscience.iop.org
Enhancement of radiation effects by high-atomic number nanoparticles (NPs) has been
increasingly studied for its potential to improve radiotherapeutic efficacy. The underlying …
increasingly studied for its potential to improve radiotherapeutic efficacy. The underlying …
Physical basis and biological mechanisms of gold nanoparticle radiosensitization
The unique properties of nanomaterials, in particular gold nanoparticles (GNPs) have
applications for a wide range of biomedical applications. GNPs have been proposed as …
applications for a wide range of biomedical applications. GNPs have been proposed as …
Gold nanoparticles in radiotherapy and recent progress in nanobrachytherapy
M Laprise‐Pelletier, T Simão… - Advanced healthcare …, 2018 - Wiley Online Library
Over the last few decades, gold nanoparticles (GNPs) have emerged as “radiosensitizers” in
oncology. Radiosensitizers are additives that can enhance the effects of radiation on …
oncology. Radiosensitizers are additives that can enhance the effects of radiation on …
Chemical enhancement by nanomaterials under X-ray irradiation
NN Cheng, Z Starkewolf, RA Davidson… - Journal of the …, 2012 - ACS Publications
We report here a new phenomenon of dynamic enhancement of chemical reactions by
nanomaterials under hard X-ray irradiation. The nanomaterials were gold and platinum …
nanomaterials under hard X-ray irradiation. The nanomaterials were gold and platinum …
Optimising element choice for nanoparticle radiosensitisers
There is considerable interest in the use of heavy atom nanoparticles as theranostic contrast
agents due to their high radiation cross-section compared to soft tissue. However, published …
agents due to their high radiation cross-section compared to soft tissue. However, published …
Monte Carlo investigation of the increased radiation deposition due to gold nanoparticles using kilovoltage and megavoltage photons in a 3D randomized cell model
Purpose: Investigation of increased radiation dose deposition due to gold nanoparticles
(GNPs) using a 3D computational cell model during x‐ray radiotherapy. Methods: Two GNP …
(GNPs) using a 3D computational cell model during x‐ray radiotherapy. Methods: Two GNP …
LET-dependent radiosensitization effects of gold nanoparticles for proton irradiation
S Li, S Penninckx, L Karmani, AC Heuskin… - …, 2016 - iopscience.iop.org
The development of new modalities and protocols is of major interest to improve the
outcome of cancer treatment. Given the appealing physical properties of protons and the …
outcome of cancer treatment. Given the appealing physical properties of protons and the …
Cancer treatment using different shapes of gold-based nanomaterials in combination with conventional physical techniques
The conventional methods of cancer treatment and diagnosis, such as radiotherapy,
chemotherapy, and computed tomography, have developed a great deal. However, the …
chemotherapy, and computed tomography, have developed a great deal. However, the …
Optimal energy for cell radiosensitivity enhancement by gold nanoparticles using synchrotron-based monoenergetic photon beams
Gold nanoparticles have been shown to enhance radiation doses delivered to biological
targets due to the high absorption coefficient of gold atoms, stemming from their high atomic …
targets due to the high absorption coefficient of gold atoms, stemming from their high atomic …
Radiosensitization by gold nanoparticles: impact of the size, dose rate, and photon energy
KV Morozov, MA Kolyvanova, ME Kartseva… - Nanomaterials, 2020 - mdpi.com
Gold nanoparticles (GNPs) emerged as promising antitumor radiosensitizers. However, the
complex dependence of GNPs radiosensitization on the irradiation conditions remains …
complex dependence of GNPs radiosensitization on the irradiation conditions remains …