An accelerated de novo lipogenesis (DNL) flux is a common characteristic of cancer cells
required to sustain a high proliferation rate. The DNL enzyme fatty acid synthase (FASN) is …

Platelets are known to enhance the wound-healing activity of mesenchymal stem cells
(MSCs). However, the mechanism by which platelets improve the therapeutic potential of …

Simple Summary This review discusses the synthesis and significance of fatty acids,
glycerophospholipids, and triacylglycerol in glioblastoma. The focus is on all enzymes …

Pancreatic ductal adenocarcinoma (PDAC) is a lethal malignancy. Long non‐coding RNAs
(lncRNAs) are important regulators in pathological processes, yet their potential roles in …

Glioblastoma is a deadly brain tumor for which there is no cure. The presence of
glioblastoma stem-like cells (GSCs) contributes to the heterogeneous nature of the disease …

Breast cancer as most often women's cancer is the second cause of mortality worldwide.
Research interest increased in testing non-standard drugs to suppress breast cancer …

Simple Summary Metabolic reprogramming in glioblastoma is a hallmark of malignancy.
Metabolic enzymes and metabolites participate in energetic metabolism and function as …

During metabolic reprogramming, glioma cells and their initiating cells efficiently utilized
carbohydrates, lipids and amino acids in the hypoxic lesions, which not only ensured …

Glioblastoma (GBM) diffusely infiltrates the brain and intermingles with non-neoplastic brain
cells, including astrocytes, neurons and microglia/myeloid cells. This complex mixture of cell …

Upregulation of fatty acid synthase (FASN) is a common event in cancer, although its
mechanistic and potential therapeutic roles are not completely understood. In this study, we …