Pharmacokinetic, pharmacodynamic and formulations aspects of Naringenin: An update

R Joshi, YA Kulkarni, S Wairkar - Life sciences, 2018 - Elsevier
Phenolic compounds constitute one of the important classes of secondary metabolites in the
plants. Flavonoids are primary phenolic compounds found in natural drugs. Naringenin is a …

[HTML][HTML] Antidiabetic properties of naringenin: A citrus fruit polyphenol

DJ Den Hartogh, E Tsiani - Biomolecules, 2019 - mdpi.com
Type 2 diabetes mellitus (T2DM) is a metabolic disease characterized by insulin resistance
and hyperglycemia and is associated with personal health and global economic burdens …

Bioavailability of hesperidin and its aglycone hesperetin—compounds found in citrus fruits as a parameter conditioning the pro-health potential (neuroprotective and …

K Wdowiak, J Walkowiak, R Pietrzak, A Bazan-Woźniak… - Nutrients, 2022 - mdpi.com
Hesperidin and hesperetin are polyphenols that can be found predominantly in citrus fruits.
They possess a variety of pharmacological properties such as neuroprotective and …

[HTML][HTML] Antihyperglycemic effect of hesperetin, a citrus flavonoid, extenuates hyperglycemia and exploring the potential role in antioxidant and antihyperlipidemic in …

R Jayaraman, S Subramani, SHS Abdullah… - Biomedicine & …, 2018 - Elsevier
Abstracts Diabetes is the major health problem in modern civilization which occurs due to
inadequate metabolism of carbohydrate and lipid could cause tremendous changes in the …

Antidiabetic Potency, Antioxidant Effects, and Mode of Actions of Citrus reticulata Fruit Peel Hydroethanolic Extract, Hesperidin, and Quercetin in Nicotinamide …

AM Ali, MA Gabbar, SM Abdel-Twab… - Oxidative medicine …, 2020 - Wiley Online Library
This study is aimed at assessing the antihyperglycemic, antihyperlipidemic, and antioxidant
effects of Citrus reticulata (C. reticulata) fruit peel hydroethanolic extract and two flavonoids …

Navel orange peel hydroethanolic extract, naringin and naringenin have anti-diabetic potentials in type 2 diabetic rats

OM Ahmed, MA Hassan, SM Abdel-Twab… - Biomedicine & …, 2017 - Elsevier
Abstract The therapy of Type 2 Diabetes Mellitus (T2DM) stays a challenging issue. During
the last decade, there has been an interest in the expansion of anti-diabetic drugs especially …

Naringin and Hesperidin Counteract Diclofenac‐Induced Hepatotoxicity in Male Wistar Rats via Their Antioxidant, Anti‐Inflammatory, and Antiapoptotic Activities

RA Hassan, WG Hozayen, HT Abo Sree… - Oxidative medicine …, 2021 - Wiley Online Library
This study is aimed at evaluating the preventive effect and at suggesting the mode of actions
of naringin and hesperidin and their combination in diclofenac‐induced hepatotoxicity. Male …

Sweet and bitter oranges: An updated comparative review of their bioactives, nutrition, food quality, therapeutic merits and biowaste valorization practices

MA Farag, B Abib, L Ayad, AR Khattab - Food Chemistry, 2020 - Elsevier
Sweet and bitter oranges are two of the most commercially-important fruit with a total world
production of 75.4 Mt, well-recognized for their unique sensory characters in addition to …

Therapeutic potential of naringin in neurological disorders

S Ahmed, H Khan, M Aschner, MM Hasan… - Food and Chemical …, 2019 - Elsevier
Neurological illnesses are multifactorial incurable debilitating disorders that may cause
neurodegeneration. These diseases influence approximately 30 million people around the …

Hesperetin, a citrus flavonoid, attenuates testicular damage in diabetic rats via inhibition of oxidative stress, inflammation, and apoptosis

A Samie, R Sedaghat, T Baluchnejadmojarad… - Life sciences, 2018 - Elsevier
Aim This study was designed to assess the beneficial effect of hesperetin on diabetes-
associated testicular injury in the rat. Main methods Oral treatment with hesperetin started 10 …