Primary hepatocytes and their cultures are a simple but versatile, well-controlled, and
relatively easy to handle in vitro system that is well-accepted for investigating xenobiotic …

Isolated liver cells (primarily isolated hepatocytes) have found important applications in
science and medicine over the past 40 years in a wide range of areas, including …

Hepatocytes are parenchymal cells of the liver and engage multiple metabolic functions,
including synthesis and secretion of proteins essential for systemic energy homeostasis …

The outcome of immunological assays is markedly influenced by the method of isolation of
lymphocytes. It is, therefore, important to comparatively assess various techniques of …

Hepatocyte transplantation is a promising method for supporting hepatic function in a broad
spectrum of liver diseases. The aim of this work was to test the efficacy of human fetal liver …

Hepatocytes, the major epithelial cells of the liver, maintain their morphology in culture
dishes coated with extracellular matrix (ECM) components such as collagen and fibronectin …

BACKGROUND: The possible modulation of receptor-mediated endocytosis (RME) by sex
steroids is not well understood, especially in terms of the different receptor–ligand systems …

The liver is a unique organ that is endowed with a plethora of specialized functions. Most of
its functional traits are controlled by hepatocytes. Primary hepatocytes have been used …

Bikunin is a chondroitin sulfate-containing plasma protein synthesized in the liver. In vitro, it
has been shown to inhibit proteases and to have additional activities, but its biological …

Abstract Background and Aim: Chronic liver failure results in the decrease of the number of
functioning hepatocytes. It dictates the necessity of using exogenous viable cells or/and …