Tuberculous meningitis is a devastating brain infection that is caused by Mycobacterium
tuberculosis and is notoriously difficult to diagnose and treat. New technologies …

Background Xpert MTB/RIF Ultra (Xpert Ultra) and Xpert MTB/RIF are World Health
Organization (WHO)‐recommended rapid nucleic acid amplification tests (NAATs) widely …

Summary Background Xpert MTB/RIF Ultra (Xpert Ultra) might have higher sensitivity than its
predecessor, Xpert MTB/RIF (Xpert), but its role in tuberculous meningitis diagnosis is …

Introduction Tuberculous meningitis accounts for 1–5% of tuberculosis cases. Diagnostic
delay contributes to poor outcomes. We evaluated the performance of the new Xpert …

Tuberculous meningitis (TBM) is the most lethal and disabling form of tuberculosis. In 2017,
approximately 10 million people developed TB worldwide, of whom more than 100,000 new …

Introduction Tuberculosis (TB) remains a major global health burden. There still remains a
large gap between the notified and estimated incident cases. Extrapulmonary (EP) TB …

Among the challenges in controlling tuberculosis, a rapid and accurate diagnostic test for the
detection of Mycobacterium tuberculosis complex (MTB c) and its resistance to first line …

Abstract Objectives The re-engineered Xpert MTB/RIF Ultra (Xpert Ultra) assay was
developed due to the poor sensitivity of the Xpert MTB/RIF assay for the detection of …

The delayed diagnosis of tuberculous meningitis (TBM) leads to poor outcomes, yet the
current diagnostic methods for identifying Mycobacterium tuberculosis in cerebrospinal fluid …

The diagnosis of extrapulmonary tuberculosis (EPTB) is often challenging due to
paucibacillary nature of the disease. Xpert MTB/RIF Ultra (Ultra) has been developed to …